Reviewed, UniProtKB/Swiss-Prot Q54B65 (SF3A2_DICDI)

Names and origin

Protein names

Recommended name:
    Splicing factor 3A subunit 2

Gene names

Name:	sf3a2
ORF Names:	DDB_0233181

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA By similarity.
Subunit structure	Component of splicing factor SF3A which is composed of three subunits By similarity.
Subcellular location	NucleusBy similarity.
Sequence similarities	Belongs to the SF3A2 family. Contains 1 matrin-type zinc finger.

Ontologies

Keywords
Biological process	mRNA processing mRNA splicing
Cellular component	Nucleus Spliceosome
Domain	Zinc-finger
Ligand	Metal-binding Zinc
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 215	215	Splicing factor 3A subunit 2
Regions
	Zinc finger	50 – 80	31	Matrin-type

Sequences

	Sequence		Length	Mass (Da)
	Q54B65-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 1EB76C7EC93E895B	FASTA	215	25,071
	10 20 30 40 50 60 MSEYGKAGSG GLQSSQYDNI DRRERQKQLV LEHVDVSKDP YIISNHIGSF ECRLCLTVHN 70 80 90 100 110 120 NVGNYLAHTQ GKKHQTHLAR RAAKEQRENP SVSKNNYIQT TRVIHKKTIK IGRPGYKIIK 130 140 150 160 170 180 QRDSKTGQLS LLFQIDYPEI ESGLQPRHRI MSAFEQRVEQ PNKDYQYLLF AAEPYETIAF 190 200 210 KIPNKEIDRT TGPDGKFFTH WDRNKTFTLQ LYFKE

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000223 Genomic DNA. Translation: EAL60509.1.
RefSeq	XP_628923.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3385584.
KEGG	ddi:DDB_0233181.
Organism-specific databases
dictyBase	DDB0233181. sf3a2.
Family and domain databases
InterPro	IPR015880. Znf_C2H2-like. IPR003604. Znf_U1. [Graphical view]
SMART	SM00355. ZnF_C2H2. 1 hit. SM00451. ZnF_U1. 1 hit. [Graphical view]
PROSITE	PS50171. ZF_MATRIN. False negative. [Graphical view]
ProDom	Q54B65. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

SF3A2_DICDI

Accession

Primary (citable) accession number: Q54B65

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	May 24, 2005
Last modified:	July 22, 2008
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)