Reviewed, UniProtKB/Swiss-Prot Q54BI5 (WDR53_DICDI)

Names and origin

Protein names

Recommended name:
    WD repeat-containing protein 53 homolog

Gene names

Name:	wdr53
ORF Names:	DDB_0266374

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	368 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the WD repeat WDR53 family. Contains 6 WD repeats.

Ontologies

Keywords
Domain	Repeat WD repeat
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 368	368	WD repeat-containing protein 53 homolog
Regions
	Repeat	27 – 66	40	WD 1
	Repeat	71 – 108	38	WD 2
	Repeat	116 – 155	40	WD 3
	Repeat	159 – 199	41	WD 4
	Repeat	228 – 267	40	WD 5
	Repeat	271 – 315	45	WD 6
	Compositional bias	7 – 19	13	Poly-Asn
	Compositional bias	215 – 219	5	Poly-Gln

Sequences

	Sequence		Length	Mass (Da)
	Q54BI5-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 8E94C06A445D6665	FASTA	368	41,988
	10 20 30 40 50 60 MTSVDINNNN NNNNNSNSNI IETKLIGHKD TVLCISSHNK KEIIASGSDD CTVRIWDLNT 70 80 90 100 110 120 NKSIQSIVEG FQGNPVNNVC FDQDFTLYCS YDNIIVSFDL RQPNVILKEF NTQYKFNTEE 130 140 150 160 170 180 INQLSFDSKY QYLAACDDSG QTKIIDVTKN KLVESLNKKH TNIATGCVFR PNSKNELITS 190 200 210 220 230 240 SMDFSIIHWD FLKAKVLHRD TFKEGSLPQN ISKSQQQQQE TTEPNRMLNP PFVTSVDCSN 250 260 270 280 290 300 NSKYVAISMG DGTIVINEIS SFKQYLKINS IHKSSIQQVH YPKYLENNYQ RLISFGNYDK 310 320 330 340 350 360 KIVIWDVSED MNTKVSSSLL SNDEKNNERI KTWLEHSEKI NCLTTSNLKN NAIFVADLSN DLKLLSIQ

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000218 Genomic DNA. Translation: EAL60616.1.
RefSeq	XP_629044.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3385666.
KEGG	ddi:DDBDRAFT_0192041.
Organism-specific databases
dictyBase	DDB0266374. wdr53.
Family and domain databases
InterPro	IPR015943. WD40/YVTN_repeat-like. IPR001680. WD40_repeat. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
Pfam	PF00400. WD40. 2 hits. [Graphical view]
PRINTS	PR00320. GPROTEINBRPT.
ProDom	PD000018. WD40. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00320. WD40. 6 hits. [Graphical view]
PROSITE	PS00678. WD_REPEATS_1. 1 hit. PS50082. WD_REPEATS_2. 1 hit. PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

WDR53_DICDI

Accession

Primary (citable) accession number: Q54BI5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	May 24, 2005
Last modified:	July 22, 2008
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)