Reviewed, UniProtKB/Swiss-Prot Q54BL2 (EFS2_DICDI)

Names and origin

Protein names

Recommended name:
    Putative pre-rRNA-processing protein esf2

Gene names

Name:	esf2
ORF Names:	DDB_0266368

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	296 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	May be involved in the small subunit (SSU) processome assembly and function, and in the 17S rRNA synthesis By similarity.
Subunit structure	Component of the 90S pre-ribosomes By similarity.
Subcellular location	Nucleus › nucleolusBy similarity.
Sequence similarities	Belongs to the ESF2/ABP1 family. Contains 1 RRM (RNA recognition motif) domain.

Ontologies

Keywords
Biological process	Ribosome biogenesis rRNA processing
Cellular component	Nucleus
Ligand	RNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 296	296	Putative pre-rRNA-processing protein esf2
Regions
	Domain	110 – 193	84	RRM
	Compositional bias	48 – 56	9	Poly-Glu

Sequences

	Sequence		Length	Mass (Da)
	Q54BL2-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 9F9F5F4963BA3FBD	FASTA	296	35,333
	10 20 30 40 50 60 MAQKRKNDKI ETSKKEEIDP RFVNKFEDLE ENDFKDDDED DFINDVNEGE EEEEEEDNED 70 80 90 100 110 120 NIEFNQEEDD EDEDDEENKD NKNKIKKVIK IKPMDIEKMK KLKEQNENKG IIYLSTIPSR 130 140 150 160 170 180 MKPAKLKQLL AKYGKVTRMH LVRANVERKN HRNDMFKEGW IEFEDKALAR KIATILNNIP 190 200 210 220 230 240 MGGKARDIHK DCLWNLRYLP KFKWHHLQDK LVSQRMERDK KLRLEINQVR KQNLILLEQV 250 260 270 280 290 ELSKHVNQKH ESKGKPIKEK VVRTFKQRSS HEDSLNSNIS SKVLEKVVSN KKQKIN

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000218 Genomic DNA. Translation: EAL60600.1.
RefSeq	XP_629017.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3385685.
KEGG	ddi:DDBDRAFT_0192016.
Organism-specific databases
dictyBase	DDB0266368. esf2.
Family and domain databases
InterPro	IPR012677. a_b_plait_nuc_bd. IPR000504. RRM_RNP1. [Graphical view]
Gene3D	G3DSA:3.30.70.330. a_b_plait_nuc_bd. 1 hit.
SMART	SM00360. RRM. 1 hit. [Graphical view]
PROSITE	PS50102. RRM. 1 hit. [Graphical view]
ProDom	Q54BL2. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

EFS2_DICDI

Accession

Primary (citable) accession number: Q54BL2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	May 24, 2005
Last modified:	July 22, 2008
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)