Reviewed, UniProtKB/Swiss-Prot Q54HF0 (ACT25_DICDI)

Names and origin

Protein names

Recommended name:
    Putative actin-25

Gene names

Name:	act25
ORF Names:	DDB_G0289507

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction By similarity.
Subcellular location	Cytoplasm › cytoskeletonBy similarity.
Sequence similarities	Belongs to the actin family.

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW cytoskeleton Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro protein binding Inferred from electronic annotation. Source: InterPro structural molecule activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 385	385	Putative actin-25		PRO_0000312675

Sequences

	Sequence		Length	Mass (Da)
	Q54HF0-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 0A229EF7C73925E1	FASTA	385	43,215
	10 20 30 40 50 60 MECEEVQAIV IDNGSSVCKA GFGGDDAPRT AFPSIVGRPR CTGFIVDMDK KDSYFCKKNS 70 80 90 100 110 120 CFMGQKDLYI GDEAQSKRGI LNVKYPIERG IITNWNDMEE IWYHTFYNEL HVAPEEHPVL 130 140 150 160 170 180 LTEPPLNPKA NREKMTQIMF ETFKTPAIYV ANQGVLSLYS TGLTTGIVMN SGDGVSHTVP 190 200 210 220 230 240 VYEGYILRQA ILSLDLAGRD LTDYMNELLT DRGYYFTTKG EKEIVRGIKE KLSYVALDFE 250 260 270 280 290 300 AEMQIASASP ALEKSYELPD GQVITIGNER FRCPEALFRP YTGIHETIYN SIMKCDDDIR 310 320 330 340 350 360 KDLFGSVVLS GGSTMFPGIV DRMNKELTAL APSTMKIKII APPERKYSVW IGGSILASLS 370 380 SFQPRWISKE EYDESGPSIV HRKCF

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000141 Genomic DNA. Translation: EAL62685.1.
RefSeq	XP_636188.1.
3D structure databases
SMR	Q54HF0. Positions 5-385.
ModBase	Search...
Genome annotation databases
GeneID	3387762.
KEGG	ddi:DDB_0220463.
Organism-specific databases
dictyBase	DDB_G0289507. act25.
Family and domain databases
InterPro	IPR004001. Actin_CS. IPR004000. Actin_like. [Graphical view]
PANTHER	PTHR11937. Actin_like. 1 hit.
Pfam	PF00022. Actin. 1 hit. [Graphical view]
PRINTS	PR00190. ACTIN.
SMART	SM00268. ACTIN. 1 hit. [Graphical view]
PROSITE	PS00406. ACTINS_1. 1 hit. PS00432. ACTINS_2. 1 hit. PS01132. ACTINS_ACT_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACT25_DICDI

Accession

Primary (citable) accession number: Q54HF0

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	May 24, 2005
Last modified:	December 16, 2008
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)