Reviewed, UniProtKB/Swiss-Prot Q54HF1 (ACT24_DICDI)

Names and origin

Protein names

Recommended name:
    Putative actin-24

Gene names

Name:	act24
ORF Names:	DDB_0220462

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	377 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction By similarity.
Subcellular location	Cytoplasm › cytoskeletonBy similarity.
Sequence similarities	Belongs to the actin family.

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton
Ligand	ATP-binding Nucleotide-binding
Molecular function	Structural protein
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 377	377	Putative actin-24

Sequences

	Sequence		Length	Mass (Da)
	Q54HF1-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 67AC474048E0ED59	FASTA	377	42,138
	10 20 30 40 50 60 MECKEDLTIV IDNGSGMCKA GFAGYDAPHA VFPSIVGRPR HTGVMVGMGQ KDSYIGDEAQ 70 80 90 100 110 120 SKRDILNLKF PVERGIITNW NDMEEIWHHT FYNELRVAPE EHPVLLTEPP LNSKANREKM 130 140 150 160 170 180 PQIMFETFNT PAMYVAIQAV LSLYASGRAT GVILDSGDGV SYTVPVYEGN TFPLSITRLH 190 200 210 220 230 240 LAGGDLTDYM SRLLYTDCGY YFSTKAEKEI VKDIKEKLAY VALDFEAEMQ TAASSPSLEK 250 260 270 280 290 300 SYKLPDGRMI TIGNERFRCP EALFQPSLLA MDYDGIHETT YNSIMKCDVD FHKDLYGNVL 310 320 330 340 350 360 LSGGSTMFPG IADRMNKELT ALAPSTMKIK IIAPPERKYS AWIGGSILAS LSSFQPRWIS 370 KEEYDESGPS IVHRKCW

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000141 Genomic DNA. Translation: EAL62684.1.
RefSeq	XP_636187.1.
3D structure databases
SMR	Q54HF1. Positions 9-377.
ModBase	Search...
Genome annotation databases
GeneID	3387761.
KEGG	ddi:DDB_0220462.
Organism-specific databases
dictyBase	DDB0220462. act24.
Family and domain databases
InterPro	IPR004001. Actin_CS. IPR004000. Actin_like. [Graphical view]
PANTHER	PTHR11937. Actin_like. 1 hit.
Pfam	PF00022. Actin. 1 hit. [Graphical view]
PRINTS	PR00190. ACTIN.
SMART	SM00268. ACTIN. 1 hit. [Graphical view]
PROSITE	PS00406. ACTINS_1. 1 hit. PS00432. ACTINS_2. 1 hit. PS01132. ACTINS_ACT_LIKE. 1 hit. [Graphical view]
ProDom	Q54HF1. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

ACT24_DICDI

Accession

Primary (citable) accession number: Q54HF1

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	May 24, 2005
Last modified:	September 23, 2008
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)