Reviewed, UniProtKB/Swiss-Prot Q54HM0 (ABCGG_DICDI)

Names and origin

Protein names

Recommended name:
    ABC transporter G family member 16

Gene names

Name:	abcG16
ORF Names:	DDB_G0289331

Organism

Dictyostelium discoideum (Slime mold)

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	1528 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane proteinBy similarity.
Sequence similarities	Belongs to the ABC transporter family. PDR subfamily. Contains 2 ABC transmembrane type-2 domains. Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane
Domain	Repeat Transmembrane
Ligand	ATP-binding Nucleotide-binding
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1528	1528	ABC transporter G family member 16		PRO_0000330365
Regions
	Transmembrane	514 – 534	21	Potential
	Transmembrane	545 – 565	21	Potential
	Transmembrane	598 – 618	21	Potential
	Transmembrane	625 – 645	21	Potential
	Transmembrane	655 – 675	21	Potential
	Transmembrane	763 – 783	21	Potential
	Transmembrane	1225 – 1245	21	Potential
	Transmembrane	1255 – 1272	18	Potential
	Transmembrane	1285 – 1305	21	Potential
	Transmembrane	1334 – 1354	21	Potential
	Transmembrane	1361 – 1381	21	Potential
	Transmembrane	1391 – 1411	21	Potential
	Transmembrane	1504 – 1524	21	Potential
	Domain	167 – 412	246	ABC transporter 1
	Domain	495 – 705	211	ABC transmembrane type-2 1
	Domain	837 – 1085	249	ABC transporter 2
	Domain	1231 – 1441	211	ABC transmembrane type-2 2
	Nucleotide binding	205 – 212	8	ATP 1 Potential
	Nucleotide binding	878 – 885	8	ATP 2 Potential
	Compositional bias	27 – 31	5	Poly-Gln
	Compositional bias	86 – 89	4	Poly-Val
	Compositional bias	483 – 486	4	Poly-Gln
	Compositional bias	1126 – 1201	76	Asn-rich
Experimental info
	Sequence conflict	378	1	L → I in AAL91501. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q54HM0-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: A9FB1710B0281B33	FASTA	1,528	172,667
	10 20 30 40 50 60 MKLTNSISPT NLDGEINKNS QPSNDNQQQQ QPKINKIINK FSESINSVSK TIGKGIGDLT 70 80 90 100 110 120 SSNALDEHIK NHNSNFIDPF YNEEAVVVVD DENIRSLIGD NCSSIGNIGV NGIEAFYGEH 130 140 150 160 170 180 NNKKSELIKQ FLKINSTNNK SNQTIVVDHM DYSVMERQSS SSSSSSSRST GVSKLIPFLK 190 200 210 220 230 240 RKEKIEILKD LSFYLKPGMM VLLLSEAGSG VSTLFKCLTN RIPKRGSING DILFDNEPID 250 260 270 280 290 300 GESHHSQYLF VQQSDHHIST LTVKETLEFS IECQSNLSRE AKKQLSSNIL SILGISHVAD 310 320 330 340 350 360 TYIGNQSIRG ISGGQKKRMT VAVELVKGAK AIMIDQATNG LDSTSAFELL NSIQMISKVS 370 380 390 400 410 420 NVPALVSLLQ PSPEIFSLFS HILMMKDGEI TFFGEKHQIF DHFSDYGLEC KDKQNPAEFL 430 440 450 460 470 480 SSIYHQAQLD PDCQLKSSSD FIVAYKQSQY YKDCLIKISQ ERLSNHKFSG DKSIKIIENE 490 500 510 520 530 540 KEQQQQEIYQ LSLIKQIQLN LKRAFLTTIR DRASILSRVI KSSLLGLLIG TLFFQLDSSQ 550 560 570 580 590 600 KSANLLPSLS FFLLTFVVFG SLAGVGQVFS ERPVFYDQKI GKYYKSIAYF FAGLVSDLIW 610 620 630 640 650 660 NFIDVIIFCS ISYWLIGLNH SADRFFFFLL AIYLLDCLVN RVSKMVSIYS PNAAIASTIA 670 680 690 700 710 720 PLYFSLFLLM AGYLIHRNSI PIYWRWMHYI SPFKWVFEAI LSNQLHGQTF TCKSDELLPP 730 740 750 760 770 780 IGYPLLNVSF PDGYSGSQVC PIIDGIEILK SKDINSDYSY KYYSVWIILS MYLLFSILSI 790 800 810 820 830 840 IGLSNITFDN IISNKEKNNG NGNNNYNGKE SINEESIKLS IKQHQQKQFE SNEKCYLTFK 850 860 870 880 890 900 NLTYKVLIKK KNHQKVSRTL LHDINGYVKP GSMVALIGSS GAGKSTLLDI LANRKDQGII 910 920 930 940 950 960 SGEILLNGKA RDKCFNRYVA YVEQEDTLPD FQTVREAITF SALLRLPNDT MTHQDKLDTV 970 980 990 1000 1010 1020 DYILDVLELN SIANTLIGKV DHGITQEQRK RVNIAIEMAS LPDILFLDEP TTGLTSVAAE 1030 1040 1050 1060 1070 1080 LIMQLIKRVA LDGRSVICTI HQPSETIFKK FDSILLLTQG GFVAYFGELG PNCRTVLNYC 1090 1100 1110 1120 1130 1140 SDLGFNCPQG KNPADFLLDF SASFNSASRL ASNDKMIPSI RSRIKNVGNY CFDGSSNLNN 1150 1160 1170 1180 1190 1200 KNEIKQQQTT TQNVNLGNED KQQQQQEEAN DDNNIQEATS SNSNNNNNND IIDNYQFSNL 1210 1220 1230 1240 1250 1260 NRDTIEIIDS GLPIGFISKT FKEKNATSFL FQFFMLLFRF FVCAIRRRNL IMTRIIRSIL 1270 1280 1290 1300 1310 1320 LSVVTGTLYL QLKNDQDGVM DRISFIFFTS TFASISCLSN IPTVFEDRFL FYHELNSNTY 1330 1340 1350 1360 1370 1380 RHLSYILAMI LADLPFTIMY SLLFSAPIYW IVGLQNDVDK FLFFIFVYYL YLQVLVSFSQ 1390 1400 1410 1420 1430 1440 LLGMVSPTLA TANEITGISF SVFSLFAGFI IKKDDIPSYY KWLNYVSITR YLVEPLTVNE 1450 1460 1470 1480 1490 1500 MTGSVSFHCE PHQLIPVPIH YTPTNATASE PTKLVFKSFC PITQGNQVLY QFDINDTDKF 1510 1520 EDTFVLIGLF IGFLLLILIF SKILKFKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evolutionary analyses of ABC transporters of Dictyostelium discoideum." Anjard C., Loomis W.F. Eukaryot. Cell 1:643-652(2002) [PubMed: 12456012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: AX4.
[2]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF482394 Genomic DNA. Translation: AAL91501.1. AAFI02000139 Genomic DNA. Translation: EAL62752.1.
RefSeq	XP_636281.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3387838.
KEGG	ddi:DDB_0191236.
Organism-specific databases
dictyBase	DDB_G0289331. abcG16.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase_core. IPR013525. ABC_2_trans. IPR003439. ABC_transporter-like. [Graphical view]
Pfam	PF01061. ABC2_membrane. 2 hits. PF00005. ABC_tran. 2 hits. [Graphical view]
ProDom	PD000006. ABC_transporter. 2 hits. [Graphical view] [Entries sharing at least one domain]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS51012. ABC_TM2. False negative. PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABCGG_DICDI

Accession

Primary (citable) accession number: Q54HM0
Secondary accession number(s): Q8T677

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 29, 2008
Last sequence update:	May 24, 2005
Last modified:	November 25, 2008
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)