Reviewed, UniProtKB/Swiss-Prot Q54NS8 (AIFB_DICDI)

Names and origin

Protein names

Recommended name:
    Apoptosis-inducing factor homolog B
    EC=1.-.-.-

Gene names

Name:	aifB
ORF Names:	DDB_0186314

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	387 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Putative FAD-dependent oxidoreductase By similarity.
Cofactor	FAD By similarity.
Sequence similarities	Belongs to the FAD-dependent oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 387	387	Apoptosis-inducing factor homolog B
Regions
	Nucleotide binding	12 – 16	5	FAD Potential
Sites
	Binding site	47	1	FAD Potential
	Binding site	292	1	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	Q54NS8-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 407FBD85043CD28B	FASTA	387	42,511
	10 20 30 40 50 60 MTSEKKRVLI IGGGYGGCEV AKQLDSKFNV TVVERKQTFF HSVGSVRAVV EPELVKKIYI 70 80 90 100 110 120 PYDKLLKNGK FIFGTVIEIS PTLAKLEDGQ ELTFDYLVIA TGSNSLAPFK APLEKKSSSE 130 140 150 160 170 180 ILNYFQNFSQ QIKQAKSILI VGGGAVACEL VSEIVEKYPV KDSELVKKIT IVHSGSKLVN 190 200 210 220 230 240 PKMNDKFTNV VSKAMKKRNV EVILNDRITM PDEIKANLLN QTSPNIQISS QNYTTEKGVP 250 260 270 280 290 300 IQADLIIWTV GIKTNSESYQ SHFSNVINES GQLKVNLSCQ VQGYNNVFAI GDCTDFDEFK 310 320 330 340 350 360 TAYNAGYHAA IAAKAIDALS KGKSNDKLAK HKVSGPILSL SLGPQDGITQ ISPTMCLGSF 370 380 ATKMIKSKSL FIDRYISQLN NPKPLIQ

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000073 Genomic DNA. Translation: EAL64966.1.
RefSeq	XP_639989.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3391073.
KEGG	ddi:DDBDRAFT_0186314.
Organism-specific databases
dictyBase	DDB0186314. aifB.
Family and domain databases
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR001100. Pyr_nuc-diS_OxRdtase. IPR001327. Pyr_OxRdtase_NAD_bd. [Graphical view]
Pfam	PF00070. Pyr_redox. 2 hits. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00411. PNDRDTASEI.
ProDom	Q54NS8. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

AIFB_DICDI

Accession

Primary (citable) accession number: Q54NS8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 29, 2008
Last sequence update:	May 24, 2005
Last modified:	September 23, 2008
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)