Reviewed, UniProtKB/Swiss-Prot Q55DB6 (AHSA_DICDI)

Names and origin

Protein names

Recommended name:
    Activator of 90 kDa heat shock protein ATPase homolog

Gene names

Name:	ahsa
Synonyms:	aha1
ORF Names:	DDB_0266643

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	383 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Cochaperone that stimulates hspD/HSP90 ATPase activity By similarity.
Subunit structure	Interacts with hspD/HSP90 By similarity.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the AHA1 family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 383	383	Activator of 90 kDa heat shock protein ATPase homolog
Regions
	Compositional bias	101 – 104	4	Poly-Pro
	Compositional bias	210 – 215	6	Poly-Gln
	Compositional bias	219 – 229	11	Poly-Thr

Sequences

	Sequence		Length	Mass (Da)
	Q55DB6-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 91EF03BD79B7F787	FASTA	383	43,082
	10 20 30 40 50 60 MAKVGEGDPR WIVENREDGH NVNGWHWSEK DCLPWSKNTI GGLFDKKVIQ ETDEYTFKIS 70 80 90 100 110 120 STPVVSGECT ANNRKGKTIF LYELDVKMNW EVVFKPKKVL PPPPTTKSKG AADDIDEEDD 130 140 150 160 170 180 DGKPAEPIIT QKKTISGEFT VPYISDENGD EAPTVRYTIN TTADNDETKQ SINMVQSLLK 190 200 210 220 230 240 SHGVPFVQSQ CQEFIKLLKK EFVSKKQVEQ SQQQQTANTT TNTTTTTNTV PKVTSSTVIF 250 260 270 280 290 300 NSTPTKKPTT KTLKLKEEFQ CSPMDAYDVF VNINKLRAFT QSDCTFENEE GGKFSLYGGS 310 320 330 340 350 360 IQGVNKTLSP GSKIVQTWRL DNWSKGVESQ VTITFSVDGK PLTNVEIVQT GIPIDEFEKT 370 380 EEGWKRNILD RIKHTFSYSS KIF

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000005 Genomic DNA. Translation: EAL72206.1.
RefSeq	XP_646215.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3397236.
KEGG	ddi:DDBDRAFT_0190493.
Organism-specific databases
dictyBase	DDB0266643. ahsa.
Family and domain databases
InterPro	IPR013538. AHSA1. IPR015310. AHSA1_N. [Graphical view]
Pfam	PF09229. Aha1_N. 1 hit. PF08327. AHSA1. 1 hit. [Graphical view]
ProDom	Q55DB6. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

AHSA_DICDI

Accession

Primary (citable) accession number: Q55DB6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 29, 2008
Last sequence update:	May 24, 2005
Last modified:	July 22, 2008
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)