SubmitCancel

Skip Header

Q56312

- CHEY_THEMA

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here

Protein
Chemotaxis protein CheY
Gene
cheY, TM_0700

Gene:

cheY, TM_0700
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed - - Experimental evidence at protein leveli

UniProt

Q56312 - CHEY_THEMA

Protein:

Chemotaxis protein CheY
Protein Existence: Experimental evidence at protein level

Functioni

Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY seems to regulate the clockwise (CW) rotation By similarity.

Cofactori

Binds 1 magnesium ion per subunit.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier
Metal bindingi91Magnesium
Metal bindingi101Magnesium
Metal bindingi541Magnesium
Metal bindingi561Magnesium; via carbonyl oxygen

GO - Molecular functioni

  1. metal ion bindingInferred from electronic annotationi Source: UniProtKB-KW
  2. phosphorelay response regulator activityInferred from electronic annotationi Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. metal ion bindingInferred from electronic annotationi Source: UniProtKB-KW
  2. phosphorelay response regulator activityInferred from electronic annotationi Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Chemotaxis, Flagellar rotation, Two-component regulatory system

Keywords - Ligandi

Magnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis protein CheY
Gene namesi
Name:cheY
Ordered Locus Names:TM_0700
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
ProteomesiUP000008183: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasmInferred from electronic annotationi Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier
Chaini1 – 120120Chemotaxis protein CheY
PRO_0000081055

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier
Modified residuei5414-aspartylphosphate

Post-translational modificationi

Phosphorylated by CheA By similarity.

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

IntActiQ56312. 1 interaction.
STRINGi243274.TM0700.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier
Beta strandi4 – 85
Helixi12 – 2413
Beta strandi28 – 358
Helixi36 – 4611
Beta strandi49 – 535
Beta strandi58 – 603
Helixi62 – 7211
Beta strandi78 – 836
Helixi87 – 9610
Beta strandi99 – 1057
Helixi108 – 11710

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TMYX-ray1.90A1-120[»]
1U0SX-ray1.90Y2-119[»]
2LLENMR-A1-103[»]
2TMYX-ray2.30A1-120[»]
3TMYX-ray2.20A/B1-120[»]
4IGAX-ray1.73A1-120[»]
4TMYX-ray2.80A/B1-120[»]
ProteinModelPortaliQ56312.
SMRiQ56312. Positions 2-119.

Miscellaneous databases

EvolutionaryTraceiQ56312.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier
Domaini1 – 119119Response regulatory

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0784.
KOiK03413.
OMAiMRMMIKN.
OrthoDBiEOG6PKFC7.
ProtClustDBiCLSK875308.

Family and domain databases

InterProiIPR011006. CheY-like_superfamily.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF00072. Response_reg. 1 hit.
[Graphical view]
SMARTiSM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF52172. SSF52172. 1 hit.
PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q56312-1 [UniParc]FASTA

« Hide

MGKRVLIVDD AAFMRMMLKD IITKAGYEVA GEATNGREAV EKYKELKPDI    50
VTMDITMPEM NGIDAIKEIM KIDPNAKIIV CSAMGQQAMV IEAIKAGAKD 100
FIVKPFQPSR VVEALNKVSK 120
Length:120
Mass (Da):13,217
Last modified:November 1, 1996 - v1
Checksum:i195AC95641264E63
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U30501 Genomic DNA. Translation: AAA96389.1.
AE000512 Genomic DNA. Translation: AAD35782.1.
PIRiB72346.
RefSeqiNP_228509.1. NC_000853.1.
YP_007977050.1. NC_021214.1.
YP_008990331.1. NC_023151.1.

Genome annotation databases

EnsemblBacteriaiAAD35782; AAD35782; TM_0700.
GeneIDi15494303.
18092089.
898367.
KEGGitma:TM0700.
tmm:Tmari_0700.
PATRICi23936318. VBITheMar51294_0712.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U30501 Genomic DNA. Translation: AAA96389.1 .
AE000512 Genomic DNA. Translation: AAD35782.1 .
PIRi B72346.
RefSeqi NP_228509.1. NC_000853.1.
YP_007977050.1. NC_021214.1.
YP_008990331.1. NC_023151.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1TMY X-ray 1.90 A 1-120 [» ]
1U0S X-ray 1.90 Y 2-119 [» ]
2LLE NMR - A 1-103 [» ]
2TMY X-ray 2.30 A 1-120 [» ]
3TMY X-ray 2.20 A/B 1-120 [» ]
4IGA X-ray 1.73 A 1-120 [» ]
4TMY X-ray 2.80 A/B 1-120 [» ]
ProteinModelPortali Q56312.
SMRi Q56312. Positions 2-119.
ModBasei Search...

Protein-protein interaction databases

IntActi Q56312. 1 interaction.
STRINGi 243274.TM0700.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD35782 ; AAD35782 ; TM_0700 .
GeneIDi 15494303.
18092089.
898367.
KEGGi tma:TM0700.
tmm:Tmari_0700.
PATRICi 23936318. VBITheMar51294_0712.

Phylogenomic databases

eggNOGi COG0784.
KOi K03413.
OMAi MRMMIKN.
OrthoDBi EOG6PKFC7.
ProtClustDBi CLSK875308.

Miscellaneous databases

EvolutionaryTracei Q56312.

Family and domain databases

InterProi IPR011006. CheY-like_superfamily.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view ]
Pfami PF00072. Response_reg. 1 hit.
[Graphical view ]
SMARTi SM00448. REC. 1 hit.
[Graphical view ]
SUPFAMi SSF52172. SSF52172. 1 hit.
PROSITEi PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publicationsDownload
  1. "Thermostable chemotaxis proteins from the hyperthermophilic bacterium Thermotoga maritima."
    Swanson R.V., Sanna M.G., Simon M.I.
    J. Bacteriol. 178:484-489(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
  2. "Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima."
    Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S.
    , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M.
    Nature 399:323-329(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
  3. "Crystal structures of CheY from Thermotoga maritima do not support conventional explanations for the structural basis of enhanced thermostability."
    Usher K.C., de la Cruz A.F.A., Dahlquist F.W., Swanson R.V., Simon M.I., Remington S.J.
    Protein Sci. 7:403-412(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS).

Entry nameiCHEY_THEMA
AccessioniPrimary (citable) accession number: Q56312
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: March 19, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi