Reviewed, UniProtKB/Swiss-Prot Q57335 (Y036_HAEIN)

Names and origin

Protein names

Recommended name:
    Uncharacterized ABC transporter ATP-binding protein HI0036

Gene names

Ordered Locus Names:

HI0036

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	592 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Cell inner membrane; Multi-pass membrane proteinPotential.
Sequence similarities	Belongs to the ABC transporter family. Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 592	592	Uncharacterized ABC transporter ATP-binding protein HI0036		PRO_0000093198
Regions
	Transmembrane	12 – 32	21	Potential
	Transmembrane	58 – 78	21	Potential
	Transmembrane	102 – 122	21	Potential
	Transmembrane	191 – 211	21	Potential
	Transmembrane	214 – 234	21	Potential
	Transmembrane	299 – 319	21	Potential
	Domain	58 – 358	301	ABC transmembrane type-1
	Domain	391 – 592	202	ABC transporter
	Nucleotide binding	424 – 431	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q57335-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 6F2E91C0C0708237	FASTA	592	67,904
	10 20 30 40 50 60 MDYSQEAITS LIWILQTLAI TSVVFSFGIF LLVRFTQWGK QFWMFAGGYL SPKRSIKPIL 70 80 90 100 110 120 FFLLIVAMTL LSVRISLVNS EWYKNMYTSL QEFNEHVFWQ QMGLFCVIAA SSVSAALVSY 130 140 150 160 170 180 YLEQRFVINW IEWLNEQLVN KWMAHRAYYK TQYLSENLDN PDQRIQQDVQ SYVKTTLSLS 190 200 210 220 230 240 TGVIDAVTSM ISYTILLWGL AGPMIVLGVE IPHMMVFLVF GYVIFTTLIA FWLGRPLISL 250 260 270 280 290 300 NFINERLNAN YRYSLIRIKE YAESIAFYAG EKVEKNQLYQ QFNAVIHNMW VIIFRTLKFS 310 320 330 340 350 360 GFNLVVSQIS VVFPLLIQVG RYFEKQIKLG DLMQTLQVFG QLHANLSFFR STYDNFASYK 370 380 390 400 410 420 ATLDRLTGFC YAIEKANNKS QTQIHNHPTD VIFKNLSIQN PLGHTLIKHL NITLPQGTSL 430 440 450 460 470 480 LIQGKSGAGK TTLLRTIAGL WSYAEGEINC PTHNQLFLSQ KPYVPQGNLM SALAYPNNAD 490 500 510 520 530 540 NISHTQAVEI LNKVQLGHLA EQLEKEQDWT RILSLGEQQR LAFARLILHK PAVAFLDEAT 550 560 570 580 590 ASMDEGLEFS MYQLLQQELP QTTIISVGHR STLKTLHQQQ LILQDKGQWQ VL

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC21714.1.
PIR	D64044.
RefSeq	NP_438209.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	950931.
GenomeReviews	Gene locus HI0036 in contig L42023_GR.
KEGG	hin:HI0036.
TIGR	HI0036.
Phylogenomic databases
HOGENOM	Q57335.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0036-MON.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase_core. IPR010509. ABC_Ald_N. IPR011527. ABC_TM_1. IPR003439. ABC_transporter-like. [Graphical view]
Pfam	PF06472. ABC_membrane_2. 1 hit. PF00005. ABC_tran. 1 hit. [Graphical view]
ProDom	PD000006. ABC_transporter. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS50929. ABC_TM1F. 1 hit. PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y036_HAEIN

Accession

Primary (citable) accession number: Q57335
Secondary accession number(s): O05006

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	November 25, 2008
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)