Reviewed, UniProtKB/Swiss-Prot Q57517 (Y053_HAEIN)

Names and origin

Protein names

Recommended name:
    Uncharacterized zinc-type alcohol dehydrogenase-like protein HI0053
    EC=1.-.-.-

Gene names

Ordered Locus Names:

HI0053

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Cofactor	Binds 2 zinc ions per subunit By similarity.
Sequence similarities	Belongs to the zinc-containing alcohol dehydrogenase family.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: InterPro
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 342	342	Uncharacterized zinc-type alcohol dehydrogenase-like protein HI0053		PRO_0000160896
Sites
	Metal binding	41	1	Zinc 1; catalytic By similarity
	Metal binding	63	1	Zinc 1; catalytic By similarity
	Metal binding	94	1	Zinc 2 By similarity
	Metal binding	97	1	Zinc 2 By similarity
	Metal binding	100	1	Zinc 2 By similarity
	Metal binding	108	1	Zinc 2 By similarity
	Metal binding	149	1	Zinc 1; catalytic By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q57517-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 100B07F9194E6954	FASTA	342	37,429
	10 20 30 40 50 60 MKERIKAICL EKPNNVVVKE VPYPEKSDND VLIQVESMGI CGSDIGAYRG TNPLVTYPRI 70 80 90 100 110 120 LGHEIVGRVI ESGIGMSDGV RVGDRVIVDP YVCCGQCYPC SIGRTNCCES LKVIGVHIDG 130 140 150 160 170 180 GMQEVIRHPA HLLTKVPDNL PIHQLPLAEP LTIALHALHR TTLKSGEHIV IIGAGAIGLM 190 200 210 220 230 240 AALAAVQYGA IPILVDILEQ RLEYAKSLGI EHIVNPHKED DIKRIKEITS GRMAEVVMEA 250 260 270 280 290 300 SGANISIKNT LHYASFAGRI ALTGWPKTET PLPTNLITFK ELNIYGSRTS KGEFEEALDM 310 320 330 340 LATNKINASH IITKCIKFEE IPSFISDLSD HPENYLKINA VF

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC21731.1.
PIR	F64141.
RefSeq	NP_438226.1.
3D structure databases
HSSP	HSSP built from PDB template 1E3J based on UniProtKB O96496.
ModBase	Search...
Genome annotation databases
GeneID	950952.
GenomeReviews	Gene locus HI0053 in contig L42023_GR.
KEGG	hin:HI0053.
NMPDR	fig|71421.1.peg.52.
TIGR	HI0053.
Phylogenomic databases
HOGENOM	Q57517.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0053-MON.
Family and domain databases
InterPro	IPR013154. AlcDHase_GroES-like. IPR002085. AlcDHase_SF_Zn. IPR013149. AlcDHase_Zn-bd. IPR002328. AlcDHase_Zn_CS. [Graphical view]
PANTHER	PTHR11695. ADH_Sf_Zn. 1 hit.
Pfam	PF08240. ADH_N. 1 hit. PF00107. ADH_zinc_N. 1 hit. [Graphical view]
PROSITE	PS00059. ADH_ZINC. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y053_HAEIN

Accession

Primary (citable) accession number: Q57517

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	November 25, 2008
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)