Reviewed, UniProtKB/Swiss-Prot Q57E91 (RPOZ_BRUAB)

Names and origin

Protein names

Recommended name:
    DNA-directed RNA polymerase subunit omega
      Short name=RNAP omega subunit
    EC=2.7.7.6
Alternative name(s):
    Transcriptase subunit omega
    RNA polymerase omega subunit

Gene names

Name:	rpoZ
Ordered Locus Names:	BruAb1_0668

Organism

Brucella abortus [Complete proteome] [HAMAP]

Taxonomic identifier

235 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	133 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits By similarity.
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
Subunit structure	The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.
Sequence similarities	Belongs to the RNA polymerase subunit omega family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transcription, DNA-dependent Inferred from electronic annotation. Source: HAMAP
Molecular function	DNA binding Inferred from electronic annotation. Source: HAMAP DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 133	133	DNA-directed RNA polymerase subunit omega		PRO_0000237440

Sequences

	Sequence		Length	Mass (Da)
	Q57E91-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 0F6191D6B99842B0	FASTA	133	14,514
	10 20 30 40 50 60 MARVTVEDCV DKVENRFELV LLAGHRARQI SQGAPITVDR DNDKNPVVAL REIADETLSP 70 80 90 100 110 120 DDLKEDLIHS LQKHVEVDEP EAAPAQIANA AEEIAEGIAE AGEEDVVTFD RMSEEELLAG 130 IEGLVAPEKN DGF

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941 / Biovar 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017223 Genomic DNA. Translation: AAX74043.1.
RefSeq	YP_221404.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3339864.
GenomeReviews	Gene locus BruAb1_0668 in contig AE017223_GR.
KEGG	bmb:BruAb1_0668.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q57E91.
Enzyme and pathway databases
BioCyc	BABO262698:BRUAB1_0668-MON.
Family and domain databases
HAMAP	MF_00366. [Tree]
InterPro	IPR003716. RNA_pol_omega. IPR006110. RNA_poly_Rpb6. [Graphical view]
Pfam	PF01192. RNA_pol_Rpb6. 1 hit. [Graphical view]
TIGRFAMs	TIGR00690. rpoZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPOZ_BRUAB

Accession

Primary (citable) accession number: Q57E91

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	May 10, 2005
Last modified:	July 22, 2008
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)