Reviewed, UniProtKB/Swiss-Prot Q57EQ8 (ACP_BRUAB)

Names and origin

Protein names

Recommended name:
    Acyl carrier protein
      Short name=ACP

Gene names

Name:	acpP
Ordered Locus Names:	BruAb1_0481

Organism

Brucella abortus [Complete proteome] [HAMAP]

Taxonomic identifier

235 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	78 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Carrier of the growing fatty acid chain in fatty acid biosynthesis By similarity.
Pathway	Lipid metabolism; fatty acid biosynthesis.
Subcellular location	CytoplasmBy similarity.
Post-translational modification	4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group By similarity.
Sequence similarities	Contains 1 acyl carrier domain.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Ligand	Phosphopantetheine
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: HAMAP cofactor binding Inferred from electronic annotation. Source: InterPro phosphopantetheine binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 78	78	Acyl carrier protein		PRO_1000066567
Sites
	Binding site	37	1	Phosphopantetheine (covalent) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q57EQ8-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 5F2933B306AEE119	FASTA	78	8,301
	10 20 30 40 50 60 MSDTAERVKK IVVEHLGVDA DKVTEGASFI DDLGADSLDT VELVMAFEEE FGVEIPDDAA 70 ETILTVGDAV KFIDKASA

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941 / Biovar 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017223 Genomic DNA. Translation: AAX73876.1.
RefSeq	YP_221237.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3339510.
GenomeReviews	Gene locus BruAb1_0481 in contig AE017223_GR.
KEGG	bmb:BruAb1_0481.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q57EQ8.
Enzyme and pathway databases
BioCyc	BABO262698:BRUAB1_0481-MON.
Family and domain databases
HAMAP	MF_01217. [Tree]
InterPro	IPR009081. ACP_like. IPR003231. Acyl_carrier. IPR006163. Phsphopanteth_bd. IPR006162. Ppantne_S. [Graphical view]
Gene3D	G3DSA:1.10.1200.10. ACP_like. 1 hit.
Pfam	PF00550. PP-binding. 1 hit. [Graphical view]
ProDom	PD000887. Acyl_carrier. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00517. acyl_carrier. 1 hit.
PROSITE	PS50075. ACP_DOMAIN. 1 hit. PS00012. PHOSPHOPANTETHEINE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACP_BRUAB

Accession

Primary (citable) accession number: Q57EQ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	May 10, 2005
Last modified:	November 25, 2008
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)