Reviewed, UniProtKB/Swiss-Prot Q57F88 (URED1_BRUAB)

Names and origin

Protein names

Recommended name:
    Urease accessory protein ureD 1

Gene names

Name:	ureD1
Synonyms:	ureD-1
Ordered Locus Names:	BruAb1_0293

Organism

Brucella abortus [Complete proteome] [HAMAP]

Taxonomic identifier

235 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	280 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter By similarity.
Subunit structure	UreD, ureF and ureG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of ureC. The ureE protein probably delivers the nickel By similarity.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the ureD family.

Ontologies

Keywords
Biological process	Nickel insertion
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	nickel ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 280	280	Urease accessory protein ureD 1		PRO_0000340417

Sequences

	Sequence		Length	Mass (Da)
	Q57F88-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 3FE5CA77016C952C	FASTA	280	30,256
	10 20 30 40 50 60 MLIINDNNLS GLSLQRVNGT GELSVQFKDG RSRISRLYQE GAAKIRMPQA VTGPLEAILI 70 80 90 100 110 120 NTSGGLTGGD RLKWDVALDD GASAVITTQA CERIYRSGGG EARIATRLKA AKGTRLAWLP 130 140 150 160 170 180 QETILFNRSI LSRRLDVELE EGAQMLVVEA TVFGRLAMGE RVVAARFADR WRVRLGGRVI 190 200 210 220 230 240 HAEEFRLGPD VGAELQAPAV AGGACAMATV LMVCEQAGRY LETARAIIGE EGGCSLWRVG 250 260 270 280 KASKLVVRLY APDSYALRRR LCPLVALLNG KAGLPKVWTI

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941 / Biovar 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017223 Genomic DNA. Translation: AAX73696.1.
RefSeq	YP_221057.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3339772.
GenomeReviews	Gene locus BruAb1_0293 in contig AE017223_GR.
KEGG	bmb:BruAb1_0293.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q57F88.
Enzyme and pathway databases
BioCyc	BABO262698:BRUAB1_0293-MON.
Family and domain databases
HAMAP	MF_01384. [Tree]
InterPro	IPR002669. UreD. [Graphical view]
Pfam	PF01774. UreD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

URED1_BRUAB

Accession

Primary (citable) accession number: Q57F88

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	May 10, 2005
Last modified:	November 25, 2008
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)