Reviewed, UniProtKB/Swiss-Prot Q57G08 (RECF_BRUAB)

Names and origin

Protein names

Recommended name:
    DNA replication and repair protein recF

Gene names

Name:	recF
Ordered Locus Names:	BruAb1_0003

Organism

Brucella abortus [Complete proteome] [HAMAP]

Taxonomic identifier

235 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	384 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	The recF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP By similarity.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the recF family.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: HAMAP SOS response Inferred from electronic annotation. Source: HAMAP
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro single-stranded DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 384	384	DNA replication and repair protein recF HAMAP MF_00365		PRO_0000236112
Regions
	Nucleotide binding	43 – 50	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q57G08-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 418A748CCCE460CC	FASTA	384	41,494
	10 20 30 40 50 60 MEAKDHIERR PDRVSIRRLK LVNFRNYAEL SLPLGPGHVV LTGENGSGKT NLIEAISFLS 70 80 90 100 110 120 PGRGLRRAAY DDVARANAEG GFAIHAALDC MIYGDAEIGT GTAGGGEGGR KVRINRIAAS 130 140 150 160 170 180 ADDLLDYARI LWVVPSMDGL FTGGASDRRR FLDRMVLAID TAHGKRVLDY EKAMRSRNRL 190 200 210 220 230 240 LNDGSNDDQW LDAIENQMAE LGTAIAAARA QAMRLIAAMI ERLPAEGPFP KADCFLEGAL 250 260 270 280 290 300 ESRIGVEAAL DLEEDFRRTL RDGRARDRAA GRTLDGPHRT DLIVQHRPKS MPAALCSTGE 310 320 330 340 350 360 QKALLIGLIL AHARLTAELS GMAPILLLDE IAAHLDMGRR AALFGILDEL GGQAFMTGTD 370 380 RALFDALAGD AQFFNVSAGQ LTGI

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941 / Biovar 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017223 Genomic DNA. Translation: AAX73426.1.
RefSeq	YP_220787.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3339566.
GenomeReviews	Gene locus BruAb1_0003 in contig AE017223_GR.
KEGG	bmb:BruAb1_0003.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q57G08.
Enzyme and pathway databases
BioCyc	BABO262698:BRUAB1_0003-MON.
Family and domain databases
HAMAP	MF_00365. [Tree]
InterPro	IPR003593. AAA+_ATPase_core. IPR001238. RecF. IPR003395. RecF/RecN/SMC_N. [Graphical view]
Pfam	PF02463. SMC_N. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
TIGRFAMs	TIGR00611. recf. 1 hit.
PROSITE	PS00617. RECF_1. 1 hit. PS00618. RECF_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECF_BRUAB

Accession

Primary (citable) accession number: Q57G08

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	May 10, 2005
Last modified:	November 25, 2008
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)