Reviewed, UniProtKB/Swiss-Prot Q58663 (LIVG_METJA)

Names and origin

Protein names

Recommended name:
    Probable branched-chain amino acid transport ATP-binding protein livG

Gene names

Name:	livG
Ordered Locus Names:	MJ1267

Organism

Methanocaldococcus jannaschii (Methanococcus jannaschii) [Complete proteome] [HAMAP]

Taxonomic identifier

2190 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Probable component of a branched-chain amino-acid transport system.
Subunit structure	Monomer.
Sequence similarities	Belongs to the ABC transporter family. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Amino-acid transport Transport
Ligand	ATP-binding Nucleotide-binding
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological process	amino acid transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 257

257

Probable branched-chain amino acid transport ATP-binding protein livG

PRO_0000092412

Regions

Domain

8 – 253

246

ABC transporter

Nucleotide binding

40 – 47

8

ATP Potential

Secondary structure

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257

Helix Strand Turn

Details...

Beta strand

6 – 17

12

Beta strand

20 – 26

7

Beta strand

29 – 31

3

Beta strand

35 – 39

5

Helix

46 – 53

8

Beta strand

60 – 66

7

Helix

76 – 82

7

Beta strand

84 – 86

3

Helix

92 – 96

5

Helix

99 – 104

6

Helix

105 – 107

3

Helix

114 – 120

7

Helix

128 – 140

13

Helix

144 – 146

3

Helix

151 – 153

3

Helix

156 – 169

14

Beta strand

173 – 179

7

Turn

180 – 183

4

Helix

186 – 201

16

Beta strand

205 – 209

5

Helix

217 – 219

3

Beta strand

221 – 227

7

Beta strand

230 – 237

8

Helix

238 – 246

9

Helix

248 – 252

5

Turn

253 – 256

4

Sequences

	Sequence		Length	Mass (Da)
	Q58663-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: B3347C3277D09C12	FASTA	257	28,995
	10 20 30 40 50 60 MRDTMEILRT ENIVKYFGEF KALDGVSISV NKGDVTLIIG PNGSGKSTLI NVITGFLKAD 70 80 90 100 110 120 EGRVYFENKD ITNKEPAELY HYGIVRTFQT PQPLKEMTVL ENLLIGEINP GESPLNSLFY 130 140 150 160 170 180 KKWIPKEEEM VEKAFKILEF LKLSHLYDRK AGELSGGQMK LVEIGRALMT NPKMIVMDEP 190 200 210 220 230 240 IAGVAPGLAH DIFNHVLELK AKGITFLIIE HRLDIVLNYI DHLYVMFNGQ IIAEGRGEEE 250 IKNVLSDPKV VEIYIGE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.
[2]	"Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter." Karpowich N., Martsinkevich O., Millen L., Yuan Y.-R., Dai P.L., MacVey K., Thomas P.J., Hunt J.F. Structure 9:571-586(2001) [PubMed: 11470432] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

L77117 Genomic DNA. Translation: AAB99273.1.

PIR

B64458.

RefSeq

NP_248263.1.

3D structure databases

PDBMSD

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1G6H	X-ray	1.60	A	1-257	[»]
1G9X	X-ray	2.60	A/B/C	1-257	[»]
1GAJ	X-ray	2.50	A	1-257	[»]

ModBase

Search...

Genome annotation databases

GeneID

1452165.

GenomeReviews

Gene locus MJ1267 in contig L77117_GR.

KEGG

mja:MJ1267.

NMPDR

fig|243232.1.peg.1300.

TIGR

MJ1267.

Phylogenomic databases

HOGENOM

Q58663.

Enzyme and pathway databases

BioCyc

MJAN243232:MJ_1267-MON.

Family and domain databases

InterPro

IPR003593. AAA+_ATPase_core.
IPR003439. ABC_transporter-like.
[Graphical view]

Pfam

PF00005. ABC_tran. 1 hit.
[Graphical view]

ProDom

PD000006. ABC_transporter. 1 hit.
[Graphical view] [Entries sharing at least one domain]

SMART

SM00382. AAA. 1 hit.
[Graphical view]

PROSITE

PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

LIVG_METJA

Accession

Primary (citable) accession number: Q58663

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 26, 2001
Last sequence update:	November 1, 1996
Last modified:	November 25, 2008
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)