Reviewed, UniProtKB/Swiss-Prot Q59001 (GLGA_METJA)

Names and origin

Protein names

Recommended name:
    Probable glycogen synthase
    EC=2.4.1.21
Alternative name(s):
    Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	MJ1606

Organism

Methanocaldococcus jannaschii (Methanococcus jannaschii) [Complete proteome] [HAMAP]

Taxonomic identifier

2190 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	521 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity.
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Caution	Could lack activity as the potential ADP-glucose binding site Arg/Lys residue in position 15 is replaced by an Ser.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 521	521	Probable glycogen synthase HAMAP MF_00484		PRO_0000188668

Sequences

	Sequence		Length	Mass (Da)
	Q59001-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 68B1E0DE40715CC2	FASTA	521	59,736
	10 20 30 40 50 60 MKIVILAPTI TPIVSYGGLG DVMRDLPKFL KKGNEVVVLT LNHYNRYFTL PYEDIKKITV 70 80 90 100 110 120 IYKGAKITFD VLRTKHPTTG VDLIVFSNES VNNLNVWDPI KYEIFADLVI TYLDEVKDID 130 140 150 160 170 180 VVSGHDWMCG LAIAKCNDIL DLPTTLTIHN EAFKGEMIEY KGEVMTFLEL GIKYADAVNT 190 200 210 220 230 240 VSPSHAEEIK NYPYIKKYLN NKPFCGILNG IDIDEYDPMK IIERMCNLSN NKLDPRNYAY 250 260 270 280 290 300 ISPYSAEDSH NIKPKIKYSW FYRGGVYEYV EDWNKIDKGI SATDVEVHGG VDGDIETPLI 310 320 330 340 350 360 GFVGRATHQK GFNTMFEAIP ELLEKHDIRF VFLTKGDRDI EERLKNLANE HDGRILALIG 370 380 390 400 410 420 YSLPLSSLVF AGSDWIIMPS YWEPCGLVQM EAMAYCTPVI ATETGGLKDT IIPLHPNPYE 430 440 450 460 470 480 HPNFDKATGV LFKVPDKVGF MWGVEHALNW TFYKLNEICM FMQYIRYKCP KHPYDENSPL 490 500 510 520 SMMMKNCYYH VFRNLSWQNS PSIRKYKGLF GGAIYNHYLQ P

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L77117 Genomic DNA. Translation: AAB99625.1.
PIR	E64500.
RefSeq	NP_248616.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1452515.
GenomeReviews	Gene locus MJ1606 in contig L77117_GR.
KEGG	mja:MJ1606.
NMPDR	fig|243232.1.peg.1653.
TIGR	MJ1606.
Phylogenomic databases
HOGENOM	Q59001.
Enzyme and pathway databases
BioCyc	MJAN243232:MJ_1606-MON.
Family and domain databases
HAMAP	MF_00484. [Tree]
InterPro	IPR001296. Glyco_trans_1. IPR013534. Glyco_transf_5. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLGA_METJA

Accession

Primary (citable) accession number: Q59001

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	July 22, 2008
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)