Unreviewed, UniProtKB/TrEMBL Q59325 (Q59325_CLOTM)

Names and origin

Protein names

Submitted name:
    Cellulose 1,4-beta-cellobiosidase EMBL CAA56918.1
    EC=3.2.1.91

Gene names

Name:

cbhA EMBL CAA56918.1

Organism

Clostridium thermocellum EMBL CAA56918.1

Taxonomic identifier

1515 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	1230 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	polysaccharide catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro cellulase activity Inferred from electronic annotation. Source: InterPro cellulose 1,4-beta-cellobiosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q59325-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: A398D9814B5D6A0E	FASTA	1,230	138,078
	10 20 30 40 50 60 MKFRRSICTA VLLAVLLTLL VPTSVFALED NSSTLPPYKN DLLYERTFDE GLCYPWHTCE 70 80 90 100 110 120 DSGGKCSFDV VDVPGQPGNK AFAVTVLDKG QNRWRVQMRH RGLTLEQGHT YRVRLKIWAD 130 140 150 160 170 180 ASCKVYIKIG QMAEPYAEYW NNKWSPYTLT AGKVLEIDET FVMDKPTDDT CEFTFHLGGE 190 200 210 220 230 240 LAATPPYTVY LDDVSLYDPE YTKPVEYILP QPDVRVNQVG YLPEGKKVAT VVCNSTQPVK 250 260 270 280 290 300 WQLKNAAGVV VLEGYTEPKG LDKDSQDYVH WLDFSDFATE GIGYYFELPT VNSPTNYSHP 310 320 330 340 350 360 FDIRKDIYTQ MKYDALAFFY HKRSGIPIEM PYAGGEQWTR PAGHIGIEPN KGDTNVPTWP 370 380 390 400 410 420 QDDEYAGIPQ KNYTKDVTGG WYDAGDHGKY VVNGGIAVWT LMNMYERAKI RGLDNWGPYR 430 440 450 460 470 480 DGGMNIPEQN NGYPDILDEA RWEIEFFKKM QVTEKEDPSI AGMVHHKIHD FRWTALGMLP 490 500 510 520 530 540 HEDPQPRYLR PVSTAATLNF AATLAQSARL WKDYDPTFAA DCLEKAEIAW QAALKHPDIY 550 560 570 580 590 600 AEYTPGSGGP GGGPYNDDYV GDEFYWAACE LYVTTGKDEY KNYLMNSPHY LEMPAKMGEN 610 620 630 640 650 660 GGANGEDNGL WGCFTWGTTQ GLGTITLALV ENGLPATDIQ KARNNIAKAA DRWLENIEEQ 670 680 690 700 710 720 GYRLPIKRAE DERAGYPWGS NSLHFEPDDL VMGYAYDFTG DSNISMECLT GISYLLGRNA 730 740 750 760 770 780 MDQSYVTGYG ERPLQNPHDR FWTPQTSKRF PAPPPGIISG RPNSRFEDPT INAAVKKDTP 790 800 810 820 830 840 PQKCFIDHTD SWSTNEITVN WNAPFAWVTA YLDEQYTDSE TDKVTIDSPV AGERFEAGKD 850 860 870 880 890 900 INIRTVKSKT PVSKVEFYNG DTLISSDTTA PYTAKITGAA VGAYNLKAVA VLSDGRRIES 910 920 930 940 950 960 PVTPVLVKVI VKPTVKLTAP KSNVVAYGNE FLKITATASD SDGKISRVDF LVDGEVIGSD 970 980 990 1000 1010 1020 REAPYEYEWK AVEGNHEISV IAYDDDDAAS TPDSVKIFVK QARDVKVQYL CENTQTSTQE 1030 1040 1050 1060 1070 1080 IKGKFNIVNT GNRDYSLKDI VLRYYFTKEH NSQLQFICYY TPIGSGNLIP SFGGSGDEHY 1090 1100 1110 1120 1130 1140 LQLEFKDVKL PAGGQTGEIQ FVIRYADNSF HDQSNDYSFD PTIKAFQDYG KVTLYKNGEL 1150 1160 1170 1180 1190 1200 VWGTPPGGTE PEEPEEPEEP EEPAIVYGDC NDDGKVNSTD VAVMKRYLKK ENVNINLDNA 1210 1220 1230 DVNADGKVNS TDFSILKRYV MKNIEELPYR

References

[1]	"Multidomain structure and cellulosomal localization of the Clostridium thermocellum cellobiohydrolase CbhA." Zverlov V.V., Velikodvorskaya G.V., Schwarz W.H., Bronnenmeier K., Kellermann J., Staudenbauer W.L. J. Bacteriol. 180:3091-3099(1998) [PubMed: 9620957] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: F7 EMBL CAA56918.1.
[2]	"Structural basis for the exocellulase activity of the cellobiohydrolase CbhA from Clostridium thermocellum." Schubot F.D., Kataeva I.A., Chang J., Shah A.K., Ljungdahl L.G., Rose J.P., Wang B.C. Biochemistry 43:1163-1170(2004) [PubMed: 14756552] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 208-818.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X80993 Genomic DNA. Translation: CAA56918.1.
PIR	S47466.
3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR012341. 6hp_glycosidase. IPR001956. CBD_3. IPR016134. Cellulos_enz_dockerin_1. IPR002105. Cellulos_enz_dockerin_1_Ca-bd. IPR003305. CenC_carb_bd. IPR002048. EF_hand_Ca_bd. IPR001701. Glyco_hydro_9. IPR004197. Glyco_hydro_9_Ig-like. IPR013783. Ig-like_fold. [Graphical view]
Gene3D	G3DSA:2.60.40.710. CBD_3. 1 hit. G3DSA:1.50.10.10. CelA/Cel48F_cat. 1 hit. G3DSA:1.10.1330.10. Cellulos_enz_dockerin_1. 1 hit. G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
PANTHER	PTHR22298:SF3. Glyco_hydro_9. 1 hit.
Pfam	PF00942. CBM_3. 1 hit. PF02018. CBM_4_9. 1 hit. PF02927. CelD_N. 1 hit. PF00404. Dockerin_1. 2 hits. PF00759. Glyco_hydro_9. 1 hit. [Graphical view]
ProDom	PD001947. CBD_3. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS51172. CBM3. 1 hit. PS00448. CLOS_CELLULOSOME_RPT. 1 hit. PS00018. EF_HAND_1. 2 hits. PS00592. GLYCOSYL_HYDROL_F9_1. 1 hit. PS00698. GLYCOSYL_HYDROL_F9_2. 1 hit. [Graphical view]

Entry information

Entry name

Q59325_CLOTM

Accession

Primary (citable) accession number: Q59325

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	November 25, 2008
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)