Reviewed, UniProtKB/Swiss-Prot Q5A6K2 (ATG22_CANAL)

Names and origin

Protein names

Recommended name:
    Autophagy-related protein 22

Gene names

Name:	ATG22
ORF Names:	CaO19.552, CaO19.8187

Organism

Candida albicans (Yeast)

Taxonomic identifier

5476 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	May be required for lysis of autophagic vesicles after delivery to the vacuole By similarity.
Subcellular location	Vacuole membrane; Multi-pass membrane proteinBy similarity. Note= Vacuole and punctate structures By similarity.
Sequence similarities	Belongs to the ATG22 family.

Ontologies

Keywords
Biological process	Autophagy Protein transport Transport
Cellular component	Membrane Vacuole
Domain	Transmembrane
PTM	Glycoprotein
Gene Ontology (GO)
Biological process	autophagy Inferred from electronic annotation. Source: UniProtKB-KW protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW vacuolar membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Autophagy-related protein 22		PRO_0000207619
Regions
	Transmembrane	108 – 128	21	Potential
	Transmembrane	137 – 157	21	Potential
	Transmembrane	164 – 184	21	Potential
	Transmembrane	209 – 229	21	Potential
	Transmembrane	244 – 264	21	Potential
	Transmembrane	304 – 324	21	Potential
	Transmembrane	339 – 359	21	Potential
	Transmembrane	368 – 388	21	Potential
	Transmembrane	438 – 458	21	Potential
	Transmembrane	467 – 487	21	Potential
Amino acid modifications
	Glycosylation	10	1	N-linked (GlcNAc...) Potential
	Glycosylation	14	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5A6K2-1 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 83F4934EBB6958FC	FASTA	500	56,532
	10 20 30 40 50 60 MKVNHNHISN TSVNNSEDVL EAQDEISNDN NKNQESIWNK KSIFHTWLLL CYSTGPVASM 70 80 90 100 110 120 SRTYIPASIQ SIAKNVGKTK MNQPCGTQGN DCYVKFGFMT VHHTSYVLYL RAVSTAIEGV 130 140 150 160 170 180 VAIFLMGIAD YSNYRKSFLI FSILVYGFLA LPFIGLTNND YQTLVLASIL YSLLIIDDSI 190 200 210 220 230 240 YQILEGSYIP LFMRADKKNP MQRGSVVAVL GLFLGNLGGI TALVIGIIIS YLSGTPESKG 250 260 270 280 290 300 YHNFLLAITI AGCLTIGLSL FSALYIPNVQ GKQRIDNFLV LPFKRFFNLL KDIQKYPMAF 310 320 330 340 350 360 LYCISWVIWN VSFNNFMSMF LLLFRSTLGL GNSDAEYTVY TFMSYICSSW GSLLWMFLYQ 370 380 390 400 410 420 KWNSNIKYWG YSFLSVSLLA NFWGCLGIHK LTPLGYQNRW EFWVFEVFYS ATSSAMRSLN 430 440 450 460 470 480 RCVYSSLLPE GNEAQYFGLE VTLGIASGWI GGLVNAVIQD RTNDDRFPFL PNMFLVVVSL 490 500 IVYYYVDLQK GKNDVNNGNS

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AACQ01000055 Genomic DNA. Translation: EAK98446.1. AACQ01000054 Genomic DNA. Translation: EAK98543.1.
RefSeq	XP_717415.1. XP_717509.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3640918. 3640951.
KEGG	cal:CaO19.552. cal:CaO19.8187.
Organism-specific databases
CGD	CAL0000232. orf19.552.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

ATG22_CANAL

Accession

Primary (citable) accession number: Q5A6K2

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	April 26, 2005
Last modified:	November 4, 2008
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)