Reviewed, UniProtKB/Swiss-Prot Q5HZH2 (CP042_MOUSE)

Names and origin

Protein names	Recommended name:     UPF0293 protein C16orf42 homolog
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	323 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Membrane; Single-pass membrane proteinPotential.
Sequence similarities	Belongs to the UPF0293 family.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 323	323	UPF0293 protein C16orf42 homolog
Regions
	Transmembrane	165 – 185	21	Potential
Experimental info
	Sequence conflict	245	1	V → E in BAB22003. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q5HZH2-1 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: CCBE907B0F811EBB	FASTA	323	35,334
	10 20 30 40 50 60 MGRKKVARGS RKESGRVRRP SGRSLDAFAE EVGAALRASV QPEEAEDQGG PGPAALPCAL 70 80 90 100 110 120 AMWELGHCDP KRCTGRKLAR LGLVRCLRLS QRFGGLVLSP VGTEYVSPAD RQLVAQSGVA 130 140 150 160 170 180 VIDCSWAKLD DTPFQKMRGS HLRLLPYLVA ANPVNYGRPC KLSCVEAFAA AFCIVGFSDL 190 200 210 220 230 240 AVILLRKFKW GKGFLDLNRE LLDKYAACRG PEEVLQAEQG YLASTRDTPE EDIDPFDVDS 250 260 270 280 290 300 GREFVNLNRP VASTRLPEDM DDTDGSEEHS EDSEEDSDEC EEPGPGANGG DSNYSGAEET 310 320 PEQEAQARDS TEIWKGIKKR QRD

References

[1]

"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J and NOD. Tissue: Kidney and Visual cortex.

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6. Tissue: Eye.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AK002309 mRNA. Translation: BAB22003.1. AK158743 mRNA. Translation: BAE34637.1. AK170074 mRNA. Translation: BAE41547.1. BC089019 mRNA. Translation: AAH89019.1.
RefSeq	NP_080952.1.
UniGene	Mm.180687
3D structure databases
ModBase	Search...
PTM databases
PhosphoSite	Q5HZH2.
Genome annotation databases
Ensembl	ENSMUSG00000015126. Mus musculus. [Contig view]
GeneID	68327.
KEGG	mmu:68327.
NMPDR	fig|10090.3.peg.2378.
Organism-specific databases
MGI	MGI:1915577. 0610007P22Rik.
Phylogenomic databases
HOVERGEN	Q5HZH2.
Gene expression databases
CleanEx	MM_0610007P22RIK.
Family and domain databases
InterPro	IPR007177. DUF367. IPR007209. RLI_metal_bd. [Graphical view]
Pfam	PF04034. DUF367. 1 hit. PF04068. RLI. 1 hit. [Graphical view]
ProDom	Q5HZH2. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

CP042_MOUSE

Accession

Primary (citable) accession number: Q5HZH2
Secondary accession number(s): Q9DD00

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 20, 2007
Last sequence update:	February 15, 2005
Last modified:	July 22, 2008
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)