Reviewed, UniProtKB/Swiss-Prot Q5JWF8 (CT134_HUMAN)

Names and origin

Protein names

Recommended name:
    Putative uncharacterized actin family protein C20orf134

Gene names

Name:

C20orf134

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	SecretedPotential.
Sequence similarities	Belongs to the actin family.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	protein binding Inferred from electronic annotation. Source: InterPro structural molecule activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 29	29	Potential
	Chain	30 – 245	216	Putative uncharacterized actin family protein C20orf134		PRO_0000232865

Sequences

	Sequence		Length	Mass (Da)
	Q5JWF8-1 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 06EC6260DF9CC2EE	FASTA	245	26,751
	10 20 30 40 50 60 MASTALLALC STGAFSGLAV EAGAGVCHAT PIYAGHSWHQ ATFRLNVAGS TLSRYLRDLL 70 80 90 100 110 120 VAANPDLLQQ ALPRKAITHL KKRSCYVSLD FEGDLRDPAR HHPASFSVGN GCCVCLSSER 130 140 150 160 170 180 FRCPEPIFQP GLLGQAEQGL PALAFRALQK MPKTLRTRLA DTVVLAGGST LFPGFAERLD 190 200 210 220 230 240 KELEAQCRRH GYAALRPHLV AKHGRGMAVW TGGSMVASLH SFQRRWITRA MYQECGSRLL YDVFN

References

[1]

"The DNA sequence and comparative analysis of human chromosome 20." Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J. Nature 414:865-871(2001) [PubMed: 11780052] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL121906 Genomic DNA. Translation: CAI22126.1.
RefSeq	NP_001019846.1.
UniGene	Hs.592151
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q5JWF8.
Genome annotation databases
Ensembl	ENSG00000182584. Homo sapiens. [Contig view]
GeneID	170487.
KEGG	hsa:170487.
Organism-specific databases
GeneCards	GC20P031719.
HGNC	HGNC:16127. C20orf134.
PharmGKB	PA25676.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	Q5JWF8.
HOVERGEN	Q5JWF8.
Gene expression databases
ArrayExpress	Q5JWF8.
CleanEx	HS_C20orf134.
GermOnline	ENSG00000182584. Homo sapiens.
Family and domain databases
InterPro	IPR004000. Actin_like. [Graphical view]
PANTHER	PTHR11937. Actin_like. 1 hit.
Pfam	PF00022. Actin. 1 hit. [Graphical view]
SMART	SM00268. ACTIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	88949.

Entry information

Entry name

CT134_HUMAN

Accession

Primary (citable) accession number: Q5JWF8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 18, 2006
Last sequence update:	February 15, 2005
Last modified:	December 16, 2008
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)