Reviewed, UniProtKB/Swiss-Prot Q5L8D1 (IF1_BACFN)

Names and origin

Protein names

Recommended name:
    Translation initiation factor IF-1

Gene names

Name:	infA
Ordered Locus Names:	BF3981

Organism

Bacteroides fragilis (strain ATCC 25285 / NCTC 9343) [Complete proteome] [HAMAP]

Taxonomic identifier

272559 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	72 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3. HAMAP MF_00075
Subcellular location	Cytoplasm. HAMAP MF_00075
Sequence similarities	Belongs to the IF-1 family. Contains 1 S1-like domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translational initiation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	RNA binding Inferred from electronic annotation. Source: HAMAP translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 72	72	Translation initiation factor IF-1 HAMAP MF_00075		PRO_0000095732
Regions
	Domain	1 – 72	72	S1-like

Sequences

	Sequence		Length	Mass (Da)
	Q5L8D1-1 [UniParc]. Last modified June 21, 2005. Version 1. Checksum: BA04DDB4D2A1D55B	FASTA	72	8,235
	10 20 30 40 50 60 MAKQSAIEQD GVIVEALSNA MFRVELENGH EITAHISGKM RMHYIKILPG DKVRVEMSPY 70 DLSKGRIVFR YK

References

[1]

"Extensive DNA inversions in the B. fragilis genome control variable gene expression." Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G., Abratt V., Lennard N., Poxton I., Duerden B., Harris B., Quail M.A., Barron A., Clark L., Corton C., Doggett J., Holden M.T.G., Larke N., Line A., Lord A. , Norbertczak H., Ormond D., Price C., Rabbinowitsch E., Woodward J., Barrell B.G., Parkhill J. Science 307:1463-1465(2005) [PubMed: 15746427] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR626927 Genomic DNA. Translation: CAH09657.1.
RefSeq	YP_213560.1.
3D structure databases
SMR	Q5L8D1. Positions 2-72.
ModBase	Search...
Genome annotation databases
GeneID	3287903.
GenomeReviews	Gene locus BF3981 in contig CR626927_GR.
KEGG	bfs:BF3981.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5L8D1.
Enzyme and pathway databases
BioCyc	BFRA272559:BF3981-MON.
Family and domain databases
HAMAP	MF_00075. [Tree]
InterPro	IPR012340. NA-bd_OB-fold. IPR006196. S1_IF1. IPR003029. S1_RNA-bd. IPR004368. TIF_IF1. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
Pfam	PF01176. eIF-1a. 1 hit. [Graphical view]
SMART	SM00316. S1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00008. infA. 1 hit.
PROSITE	PS50832. S1_IF1_TYPE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

IF1_BACFN

Accession

Primary (citable) accession number: Q5L8D1

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	June 21, 2005
Last modified:	November 4, 2008
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)