Reviewed, UniProtKB/Swiss-Prot Q5SQ80 (A20A2_HUMAN)

Names and origin

Protein names

Recommended name:
    Ankyrin repeat domain-containing protein 20A2

Gene names

Name:

ANKRD20A2

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	823 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 5 ANK repeats.

Ontologies

Keywords
Domain	ANK repeat Coiled coil Repeat
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 823	823	Ankyrin repeat domain-containing protein 20A2
Regions
	Repeat	66 – 95	30	ANK 1
	Repeat	99 – 128	30	ANK 2
	Repeat	132 – 161	30	ANK 3
	Repeat	165 – 194	30	ANK 4
	Repeat	198 – 227	30	ANK 5
	Coiled coil	431 – 480	50	Potential
	Coiled coil	565 – 724	160	Potential
	Coiled coil	776 – 805	30	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5SQ80-1 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 6C1C478C3EE9B67F	FASTA	823	94,087
	10 20 30 40 50 60 MKLFGFGSRR GQTAQGSIDH VYTGSGYRIR DSELQKIHRA AVKGDAAEVE RCLARRSGDL 70 80 90 100 110 120 DALDKQHRTA LHLACASGHV QVVTLLVNRK CQIDVCDKEN RTPLIQAVHC QEEACAVILL 130 140 150 160 170 180 EHGANPNLKD IYGNTALHYA VYSESTSLAE KLLSHGAHIE ALDKDNNTPL LFAIICKKEK 190 200 210 220 230 240 MVEFLLKRKA SSHAVDRLRR SALMLAVYYD SPGIVNILLK QNIDVFAQDM CGRDAEDYAI 250 260 270 280 290 300 SHHLTKIQQQ ILEHKKKILK KEKSDVGSSD ESAVSIFHEL RVDSLPASDD KDLNVATKQC 310 320 330 340 350 360 VPEKVSEPLP GSSHEKGNRI VNGQGEGPPA KHPSLKPSTE VEDPAVKGAV QRKNVQTLRA 370 380 390 400 410 420 EQALPVASEE EQERHERSEK KQPQVKEGNN TNKSEKIQLS ENICDSTSSA AAGRLTQQRK 430 440 450 460 470 480 IGKTYPQQFP KKLKEEHDRC TLKQENEEKT NVNMLYKKNR EELERKEKQY KKEVEAKQLE 490 500 510 520 530 540 PTVQSLEMKS KTARNTPNRD FHNHEEMKGL MDENCILKAD IAILRQEICT MKNDNLEKEN 550 560 570 580 590 600 KYLKDIKIVK ETNAALEKYI KLNEEMITET AFRYQQELND LKAENTRLNA ELLKEKESKK 610 620 630 640 650 660 RLEADIESYQ SRLAAAISKH SESVKTERNL KLALERTRDV SVQVEMSSAI SKVKDENEFL 670 680 690 700 710 720 TEQLSETQIK FNALKDKFRK TRDSLRKKSL ALETVQNDLS QTQQQTQEMK EMYQNAEAKV 730 740 750 760 770 780 NNSTGKWNCV EERICHLQRE NAWLVQQLDD VHQKEDHKEI VTNIQRGFIE SGKKDLVLEE 790 800 810 820 KSKKLMNECD HLKESLFQYE REKTEGVVSI KEDKYFQTSR KKI

References

[1]

"DNA sequence and analysis of human chromosome 9." Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I. Nature 429:369-374(2004) [PubMed: 15164053] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL773545, BX664727 Genomic DNA. Translation: CAI12706.1. BX664727, AL773545 Genomic DNA. Translation: CAI39536.1.
RefSeq	NP_001012421.1.
UniGene	Hs.632663 Hs.645502
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000183148. Homo sapiens. [Contig view]
GeneID	441430.
KEGG	hsa:441430.
Organism-specific databases
HGNC	HGNC:31979. ANKRD20A2.
GenAtlas	Search...
GeneCards	Search...
GeneLynx	Search...
Phylogenomic databases
HOGENOM	Q5SQ80.
HOVERGEN	Q5SQ80.
Gene expression databases
CleanEx	HS_ANKRD20A2.
GermOnline	ENSG00000183148. Homo sapiens.
Family and domain databases
InterPro	IPR002110. ANK. [Graphical view]
Gene3D	G3DSA:1.25.40.20. ANK. 1 hit.
Pfam	PF00023. Ank. 6 hits. [Graphical view]
PRINTS	PR01415. ANKYRIN.
SMART	SM00248. ANK. 6 hits. [Graphical view]
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 4 hits. [Graphical view]
ProDom	Q5SQ80. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

A20A2_HUMAN

Accession

Primary (citable) accession number: Q5SQ80

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	December 21, 2004
Last modified:	July 22, 2008
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)