Reviewed, UniProtKB/Swiss-Prot Q5XKK7 (CO017_HUMAN)

Names and origin

Protein names

Recommended name:
    Uncharacterized protein C15orf17

Gene names

Name:

C15orf17

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	198 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q5XKK7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q5XKK7-2)

The sequence of this isoform differs from the canonical sequence as follows:
     103-113: VKFNKGYTALS → QQAPPPLCQQL
     114-198: Missing.

Notes: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 198	198	Uncharacterized protein C15orf17
Natural variations
	Alternative sequence	103 – 113	11	VKFNKGYTALS → QQAPPPLCQQL in isoform 2.
	Alternative sequence	114 – 198	85	Missing in isoform 2.

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 09B6208FA3307A87	FASTA	198	21,103
	10 20 30 40 50 60 MATAEPSGRA LRLSTPGPRP SGARDRAPGA AGPPSGQIGN RALRLGERTP AAVEKRGPYM 70 80 90 100 110 120 VTRAPSIQAK LQKHRDLAKA VLRRKGMLGA SPNRPDSSGK RSVKFNKGYT ALSQSPDENL 130 140 150 160 170 180 VSLDSDSDGE LGSRYSSGYS SAEQVNQDVS RQLLQDGYHL DEIPDDEDLD LIPPKPMASS 190 TCSCCWCCLG DSSSCTLQ
	Isoform 2 [UniParc]. Checksum: FA727488AEE7C172		113	11,907
	10 20 30 40 50 60 MATAEPSGRA LRLSTPGPRP SGARDRAPGA AGPPSGQIGN RALRLGERTP AAVEKRGPYM 70 80 90 100 110 VTRAPSIQAK LQKHRDLAKA VLRRKGMLGA SPNRPDSSGK RSQQAPPPLC QQL

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Lung.

[2]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 3-198 (ISOFORM 2). Tissue: Spleen.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC015637 mRNA. Translation: AAH15637.1. AK000005 mRNA. Translation: BAA92230.1.
RefSeq	NP_065180.1.
UniGene	Hs.367690
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000178761. Homo sapiens. [Contig view]
GeneID	57184.
KEGG	hsa:57184.
Organism-specific databases
HGNC	HGNC:24695. C15orf17.
PharmGKB	PA134953632.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q5XKK7.
Gene expression databases
ArrayExpress	Q5XKK7.
CleanEx	HS_C15orf17.
GermOnline	ENSG00000178761. Homo sapiens.
Family and domain databases
ProDom	Q5XKK7. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

CO017_HUMAN

Accession

Primary (citable) accession number: Q5XKK7
Secondary accession number(s): Q9NXY0

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	November 23, 2004
Last modified:	July 22, 2008
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)