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Reviewed, UniProtKB/Swiss-Prot Q60348 (Y043_METJA)

Last modified July 22, 2008. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Uncharacterized protein MJ0043
Cleaved into 1 chains:
  Recommended name:
      Mja hyp1 intein
Gene names
Ordered Locus Names: MJ0043
OrganismMethanocaldococcus jannaschii (Methanococcus jannaschii) [Complete proteome] [HAMAP]
Taxonomic identifier2190 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

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Protein attributes

Sequence length785 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existencePredicted.

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General annotation (Comments)

Post-translational modification

This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation Potential.

Sequence similarities

Contains 1 DOD-type homing endonuclease domain.

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Ontologies

Keywords

   PTMAutocatalytic cleavage
Protein splicing
   Technical termComplete proteome

Gene Ontology (GO)

None. [Check GOA]

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical view

Molecule processing

Chain1 – 128128Uncharacterized protein MJ0043, 1st part Potential
Chain129 – 520392Mja hyp1 intein Potential
Chain521 – 785265Uncharacterized protein MJ0043, 2nd part Potential

Regions

Domain293 – 421129DOD-type homing endonuclease

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Sequences

Sequence LengthMass (Da)Tools
Q60348-1 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 4167A59032511F17

FASTA78591,459
        10         20         30         40         50         60 
MIANVDLHIH SRFSGGTSKD MNVENILKYG KLKGLNIIGT GDCTHPDYLE EIKQYKDREL 

        70         80         90        100        110        120 
ILTTEIEDKN RVHHLILLPS ISKVEELREI LKKYSKDIDK EGRPRVSIGG AELLEIVRDV 

       130        140        150        160        170        180 
GGLIGPAHCV PPDTLLILEN GFKRIVDIKV GDKVLTHENR FKKVEKVYKR RYIGDIIKIK 

       190        200        210        220        230        240 
VRYFPEEIIL TPEHPVYAIK TEKRCDGSHG ICKFNCLTQY TNPSCKKRYR KYKREWIIAK 

       250        260        270        280        290        300 
DLKVGDVIVY PIPNRVRDIK YLSLDKYLSN IKREFCRSRI PEKIEVSEEF CRLVGYFLSE 

       310        320        330        340        350        360 
GYCFRDGIGF ALGENEKKII DDIEYLMKKI FNLKPKIRDD GRSEGIELKY YSRVLRDFFG 

       370        380        390        400        410        420 
DMFYCGDEKR AWNKALPNEF LYLPKNKQLQ IFIGWWRGDK GVTTSEILMN QLRLISLRLG 

       430        440        450        460        470        480 
FIITFSKHVP KNPKIGDREV IKYHARWQGR VSILDEKIVD ELKNEDIKLP KKDVRYGWIK 

       490        500        510        520        530        540 
GNYLYAPIIR IGREYYDGFV YNLEVEDDSS YVTVSGTLHN CFTPWTSLYK SFDSIYDCYN 

       550        560        570        580        590        600 
KKPDFVELGL SADTDMADMI PELRDLPFLS NSDAHSYHPH RLGREFNQIE VDYIGGIEDN 

       610        620        630        640        650        660 
FEQIKKAIKH NKIIANYGLD PKLGKYHLTA CSKCHTRFKL EDAKKYNWKC PKCGGSIKKG 

       670        680        690        700        710        720 
VLSRVEELSD GKIEHPKFRP PYYKLIPLAE MISLTIGKGI FTKAVQSLWE EFIKKYGNEI 

       730        740        750        760        770        780 
EVLINADIDE LSKIHPKVAE TINLFRKGKI YIYPGGGGEY GKISFKPQKV EWYREEVTLD 


RWLKQ

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Cross-references

Sequence databases

L77117 Genomic DNA. Translation: AAB98023.1.
PIRC64305.
RefSeqNP_247006.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1450881.
GenomeReviewsGene locus MJ0043 in contig L77117_GR.
KEGGmja:MJ0043.
NMPDRfig|243232.1.peg.43.
TIGRMJ0043.

Phylogenomic databases

HOGENOMQ60348.

Enzyme and pathway databases

BioCycMJAN243232:MJ_0043-MON.

Family and domain databases

InterProIPR005287. CHP00375.
IPR003586. Hedgehog_hint_C.
IPR003587. Hedgehog_hint_N.
IPR006142. INTEIN.
IPR004042. Intein_endonuc.
IPR006141. Intein_splicing_site.
IPR004013. PHP_C.
IPR003141. PHP_N.
[Graphical view]
PfamPF02811. PHP. 1 hit.
[Graphical view]
PRINTSPR00379. INTEIN.
SMARTSM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
SM00481. POLIIIAc. 1 hit.
[Graphical view]
TIGRFAMsTIGR00375. CHP375. 1 hit.
TIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEPS50818. INTEIN_C_TER. 1 hit.
PS50819. INTEIN_ENDONUCLEASE. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
[Graphical view]
ProDomQ60348.
[Graphical view] [Entries sharing at least one domain]
BLOCKSSearch...

Other Resources

ProtoNetSearch...

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Entry information

Entry nameY043_METJA
AccessionPrimary (citable) accession number: Q60348
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 22, 2008
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

Intein-containing proteins

List of intein-containing protein entries

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents