Reviewed, UniProtKB/Swiss-Prot Q68CP9 (ARID2_HUMAN)

Names and origin

Protein names

Recommended name:
    AT-rich interactive domain-containing protein 2
Alternative name(s):
    ARID domain-containing protein 2
    BRG1-associated factor 200
      Short name=BAF200
    Zinc finger protein with activation potential
    Zipzap/p200

Gene names

Name:	ARID2
Synonyms:	KIAA1557

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1835 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.
Subunit structure	Component of the SWI/SNF-B (PBAF) chromatin remodeling complex, at least composed of SMARCA4/BRG1, SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF250B and actin. Interacts with SRF. Forms complexes with SRF and SRF cofactors MYOCD, NKX2-5 and SRFBP1.
Subcellular location	Nucleus.
Tissue specificity	Highly expressed in heart and testis.
Developmental stage	Up-regulated in adult heart (at protein level).
Sequence similarities	Contains 1 ARID domain. Contains 1 C2H2-type zinc finger.
Sequence caution	The sequence AAU20329.2 differs from that shown. Reason: Miscellaneous discrepancy. Differs from position 1094 onward for unknown reason.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Domain	Zinc-finger
Ligand	DNA-binding Metal-binding Zinc
Molecular function	Chromatin regulator
Gene Ontology (GO)
Molecular function	protein binding Ref.8 Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
PBRM1	Q86U86	2	EBI-637818,EBI-637807
SMARCA4	P51532	1	EBI-637818,EBI-302489
SMARCB1	Q12824	1	EBI-637818,EBI-358419
SMARCE1	Q969G3	1	EBI-637818,EBI-455078

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q68CP9-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q68CP9-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-883: Missing.
     884-974: PSPQASRVGF...QPNITPSSSP → MMMRYHQAIQ...SCDLKKILKS

Notes: No experimental confirmation available.

Isoform 3 (identifier: Q68CP9-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1784-1835: Missing.

Notes: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 1835	1835	AT-rich interactive domain-containing protein 2
Regions
	Domain	13 – 105	93	ARID
	Zinc finger	1632 – 1657	26	C2H2-type
	Motif	313 – 317	5	LXXL
	Compositional bias	793 – 1128	336	Gln-rich
Natural variations
	Alternative sequence	1 – 883	883	Missing in isoform 2.
	Alternative sequence	884 – 974	91	PSPQA…PSSSP → MMMRYHQAIQSHSFLLVQFH LPTITSNTVCRIICVKVMGC PWTLIRQMIIINWCFHCYLD SQMKWTLLLTYALSYQMKAS TSCDLKKILKS in isoform 2.
	Alternative sequence	1784 – 1835	52	Missing in isoform 3.
Experimental info
	Sequence conflict	169	1	L → P in CAH18689. Ref.4
	Sequence conflict	217	1	F → L in CAD91164. Ref.4
	Sequence conflict	665	1	T → I in CAD91164. Ref.4
	Sequence conflict	801	1	M → T in AAZ74794. Ref.1
	Sequence conflict	825	1	S → P in CAH18689. Ref.4
	Sequence conflict	906	1	V → F in CAD91164. Ref.4
	Sequence conflict	956	1	A → V in CAD91164. Ref.4
	Sequence conflict	988	1	M → T in CAH18689. Ref.4
	Sequence conflict	989	1	S → P in CAD97878. Ref.4
	Sequence conflict	1035	1	Q → R in BAB55320. Ref.2
	Sequence conflict	1062	1	Q → R in CAH18689. Ref.4
	Sequence conflict	1204	1	S → G in CAD97878. Ref.4
	Sequence conflict	1292	1	S → N in CAD97878. Ref.4
	Sequence conflict	1460	1	V → A in CAD97878. Ref.4
	Sequence conflict	1543	1	D → G in CAD91164. Ref.4
	Sequence conflict	1543	1	D → N in BAC87171. Ref.4
	Sequence conflict	1647	1	S → P in CAD97878. Ref.4
	Sequence conflict	1700	1	L → S in CAD91164. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified August 30, 2005. Version 2. Checksum: F540A029FA2264D4	FASTA	1,835	197,391
	10 20 30 40 50 60 MANSTGKAPP DERRKGLAFL DELRQFHHSR GSPFKKIPAV GGKELDLHGL YTRVTTLGGF 70 80 90 100 110 120 AKVSEKNQWG EIVEEFNFPR SCSNAAFALK QYYLRYLEKY EKVHHFGEDD DEVPPGNPKP 130 140 150 160 170 180 QLPIGAIPSS YNYQQHSVSD YLRQSYGLSM DFNSPNDYNK LVLSLLSGLP NEVDFAINVC 190 200 210 220 230 240 TLLSNESKHV MQLEKDPKII TLLLANAGVF DDTLGSFSTV FGEEWKEKTD RDFVKFWKDI 250 260 270 280 290 300 VDDNEVRDLI SDRNKSHEGT SGEWIWESLF HPPRKLGIND IEGQRVLQIA VILRNLSFEE 310 320 330 340 350 360 GNVKLLAANR TCLRFLLLSA HSHFISLRQL GLDTLGNIAA ELLLDPVDFK TTHLMFHTVT 370 380 390 400 410 420 KCLMSRDRFL KMRGMEILGN LCKAEDNGVL ICEYVDQDSY REIICHLTLP DVLLVISTLE 430 440 450 460 470 480 VLYMLTEMGD VACTKIAKVE KSIDMLVCLV SMDIQMFGPD ALAAVKLIEH PSSSHQMLSE 490 500 510 520 530 540 IRPQAIEQVQ TQTHVASAPA SRAVVAQHVA PPPGIVEIDS EKFACQWLNA HFEVNPDCSV 550 560 570 580 590 600 SRAEMYSEYL STCSKLARGG ILTSTGFYKC LRTVFPNHTV KRVEDSSSNG QAHIHVVGVK 610 620 630 640 650 660 RRAIPLPIQM YYQQQPVSTS VVRVDSVPDV SPAPSPAGIP HGSQTIGNHF QRTPVANQSS 670 680 690 700 710 720 NLTATQMSFP VQGVHTVAQT VSRIPQNPSP HTHQQQNAPV TVIQSKAPIP CEVVKATVIQ 730 740 750 760 770 780 NSIPQTGVPV SIAVGGGPPQ SSVVQNHSTG PQPVTVVNSQ TLLHHPSVIP QQSPLHTVVP 790 800 810 820 830 840 GQIPSGTPVT VIQQAVPQSH MFGRVQNIPA CTSTVSQGQQ LITTSPQPVQ TSSQQTSAGS 850 860 870 880 890 900 QSQDTVIIAP PQYVTTSASN IVSATSVQNF QVATGQMVTI AGVPSPQASR VGFQNIAPKP 910 920 930 940 950 960 LPSQQVSSTV VQQPIQQPQQ PTQQSVVIVS QPAQQGQTYA PAIHQIVLAN PAALPAGQTV 970 980 990 1000 1010 1020 QLTGQPNITP SSSPSPVPAT NNQVPTAMSS SSTPQSQGPP PTVSQMLSVK RQQQQQHSPA 1030 1040 1050 1060 1070 1080 PPPQQVQVQV QQPQQVQMQV QPQQSNAGVG QPASGESSLI KQLLLPKRGP STPGGKLILP 1090 1100 1110 1120 1130 1140 APQIPPPNNA RAPSPQVVYQ VASNQAAGFG VQGQTPAQQL LVGQQNVQLV PSAMPPSGGV 1150 1160 1170 1180 1190 1200 QTVPISNLQI LPGPLISNSP ATIFQGTSGN QVTITVVPNT SFAPATVSQG NATQLIAPAG 1210 1220 1230 1240 1250 1260 ITMSGTQTGV GLPVQTLPAT QASPAGQSSC TTATPPFKGD KIICQKEEEA KEATGLHVHE 1270 1280 1290 1300 1310 1320 RKIEVMENPS CRRGATNTSN GDTKENEMHV GSLLNGRKYS DSSLPPSNSG KIQSETNQCS 1330 1340 1350 1360 1370 1380 LISNGPSLEL GENGASGKQN SEQIDMQDIK SDLRKPLVNG ICDFDKGDGS HLSKNIPNHK 1390 1400 1410 1420 1430 1440 TSNHVGNGEI SPMEPQGTLD ITQQDTAKGD QLERISNGPV LTLGGSSVSS IQEASNAATQ 1450 1460 1470 1480 1490 1500 QFSGTDLLNG PLASSLNSDV PQQRPSVVVS PHSTTSVIQG HQIIAVPDSG SKVSHSPALS 1510 1520 1530 1540 1550 1560 SDVRSTNGTA ECKTVKRPAE DTDRETVAGI PNKVGVRIVT ISDPNNAGCS ATMVAVPAGA 1570 1580 1590 1600 1610 1620 DPSTVAKVAI ESAVQQKQQH PPTYVQNVVP QNTPMPPSPA VQVQGQPNSS QPSPFSGSSQ 1630 1640 1650 1660 1670 1680 PGDPMRKPGQ NFMCLWQSCK KWFQTPSQVF YHAATEHGGK DVYPGQCLWE GCEPFQRQRF 1690 1700 1710 1720 1730 1740 SFITHLQDKH CSKDALLAGL KQDEPGQAGS QKSSTKQPTV GGTSSTPRAQ KAIVNHPSAA 1750 1760 1770 1780 1790 1800 LMALRRGSRN LVFRDFTDEK EGPITKHIRL TAALILKNIG KYSECGRRLL KRHENNLSVL 1810 1820 1830 AISNMEASST LAKCLYELNF TVQSKEQEKD SEMLQ
	Isoform 2 [UniParc]. Checksum: D17D23CA87AE483F		952	101,790
	10 20 30 40 50 60 MMMRYHQAIQ SHSFLLVQFH LPTITSNTVC RIICVKVMGC PWTLIRQMII INWCFHCYLD 70 80 90 100 110 120 SQMKWTLLLT YALSYQMKAS TSCDLKKILK SSPVPATNNQ VPTAMSSSST PQSQGPPPTV 130 140 150 160 170 180 SQMLSVKRQQ QQQHSPAPPP QQVQVQVQQP QQVQMQVQPQ QSNAGVGQPA SGESSLIKQL 190 200 210 220 230 240 LLPKRGPSTP GGKLILPAPQ IPPPNNARAP SPQVVYQVAS NQAAGFGVQG QTPAQQLLVG 250 260 270 280 290 300 QQNVQLVPSA MPPSGGVQTV PISNLQILPG PLISNSPATI FQGTSGNQVT ITVVPNTSFA 310 320 330 340 350 360 PATVSQGNAT QLIAPAGITM SGTQTGVGLP VQTLPATQAS PAGQSSCTTA TPPFKGDKII 370 380 390 400 410 420 CQKEEEAKEA TGLHVHERKI EVMENPSCRR GATNTSNGDT KENEMHVGSL LNGRKYSDSS 430 440 450 460 470 480 LPPSNSGKIQ SETNQCSLIS NGPSLELGEN GASGKQNSEQ IDMQDIKSDL RKPLVNGICD 490 500 510 520 530 540 FDKGDGSHLS KNIPNHKTSN HVGNGEISPM EPQGTLDITQ QDTAKGDQLE RISNGPVLTL 550 560 570 580 590 600 GGSSVSSIQE ASNAATQQFS GTDLLNGPLA SSLNSDVPQQ RPSVVVSPHS TTSVIQGHQI 610 620 630 640 650 660 IAVPDSGSKV SHSPALSSDV RSTNGTAECK TVKRPAEDTD RETVAGIPNK VGVRIVTISD 670 680 690 700 710 720 PNNAGCSATM VAVPAGADPS TVAKVAIESA VQQKQQHPPT YVQNVVPQNT PMPPSPAVQV 730 740 750 760 770 780 QGQPNSSQPS PFSGSSQPGD PMRKPGQNFM CLWQSCKKWF QTPSQVFYHA ATEHGGKDVY 790 800 810 820 830 840 PGQCLWEGCE PFQRQRFSFI THLQDKHCSK DALLAGLKQD EPGQAGSQKS STKQPTVGGT 850 860 870 880 890 900 SSTPRAQKAI VNHPSAALMA LRRGSRNLVF RDFTDEKEGP ITKHIRLTAA LILKNIGKYS 910 920 930 940 950 ECGRRLLKRH ENNLSVLAIS NMEASSTLAK CLYELNFTVQ SKEQEKDSEM LQ
	Isoform 3 [UniParc]. Checksum: DD2BB28AF96DC860		1,783	191,422
	10 20 30 40 50 60 MANSTGKAPP DERRKGLAFL DELRQFHHSR GSPFKKIPAV GGKELDLHGL YTRVTTLGGF 70 80 90 100 110 120 AKVSEKNQWG EIVEEFNFPR SCSNAAFALK QYYLRYLEKY EKVHHFGEDD DEVPPGNPKP 130 140 150 160 170 180 QLPIGAIPSS YNYQQHSVSD YLRQSYGLSM DFNSPNDYNK LVLSLLSGLP NEVDFAINVC 190 200 210 220 230 240 TLLSNESKHV MQLEKDPKII TLLLANAGVF DDTLGSFSTV FGEEWKEKTD RDFVKFWKDI 250 260 270 280 290 300 VDDNEVRDLI SDRNKSHEGT SGEWIWESLF HPPRKLGIND IEGQRVLQIA VILRNLSFEE 310 320 330 340 350 360 GNVKLLAANR TCLRFLLLSA HSHFISLRQL GLDTLGNIAA ELLLDPVDFK TTHLMFHTVT 370 380 390 400 410 420 KCLMSRDRFL KMRGMEILGN LCKAEDNGVL ICEYVDQDSY REIICHLTLP DVLLVISTLE 430 440 450 460 470 480 VLYMLTEMGD VACTKIAKVE KSIDMLVCLV SMDIQMFGPD ALAAVKLIEH PSSSHQMLSE 490 500 510 520 530 540 IRPQAIEQVQ TQTHVASAPA SRAVVAQHVA PPPGIVEIDS EKFACQWLNA HFEVNPDCSV 550 560 570 580 590 600 SRAEMYSEYL STCSKLARGG ILTSTGFYKC LRTVFPNHTV KRVEDSSSNG QAHIHVVGVK 610 620 630 640 650 660 RRAIPLPIQM YYQQQPVSTS VVRVDSVPDV SPAPSPAGIP HGSQTIGNHF QRTPVANQSS 670 680 690 700 710 720 NLTATQMSFP VQGVHTVAQT VSRIPQNPSP HTHQQQNAPV TVIQSKAPIP CEVVKATVIQ 730 740 750 760 770 780 NSIPQTGVPV SIAVGGGPPQ SSVVQNHSTG PQPVTVVNSQ TLLHHPSVIP QQSPLHTVVP 790 800 810 820 830 840 GQIPSGTPVT VIQQAVPQSH MFGRVQNIPA CTSTVSQGQQ LITTSPQPVQ TSSQQTSAGS 850 860 870 880 890 900 QSQDTVIIAP PQYVTTSASN IVSATSVQNF QVATGQMVTI AGVPSPQASR VGFQNIAPKP 910 920 930 940 950 960 LPSQQVSSTV VQQPIQQPQQ PTQQSVVIVS QPAQQGQTYA PAIHQIVLAN PAALPAGQTV 970 980 990 1000 1010 1020 QLTGQPNITP SSSPSPVPAT NNQVPTAMSS SSTPQSQGPP PTVSQMLSVK RQQQQQHSPA 1030 1040 1050 1060 1070 1080 PPPQQVQVQV QQPQQVQMQV QPQQSNAGVG QPASGESSLI KQLLLPKRGP STPGGKLILP 1090 1100 1110 1120 1130 1140 APQIPPPNNA RAPSPQVVYQ VASNQAAGFG VQGQTPAQQL LVGQQNVQLV PSAMPPSGGV 1150 1160 1170 1180 1190 1200 QTVPISNLQI LPGPLISNSP ATIFQGTSGN QVTITVVPNT SFAPATVSQG NATQLIAPAG 1210 1220 1230 1240 1250 1260 ITMSGTQTGV GLPVQTLPAT QASPAGQSSC TTATPPFKGD KIICQKEEEA KEATGLHVHE 1270 1280 1290 1300 1310 1320 RKIEVMENPS CRRGATNTSN GDTKENEMHV GSLLNGRKYS DSSLPPSNSG KIQSETNQCS 1330 1340 1350 1360 1370 1380 LISNGPSLEL GENGASGKQN SEQIDMQDIK SDLRKPLVNG ICDFDKGDGS HLSKNIPNHK 1390 1400 1410 1420 1430 1440 TSNHVGNGEI SPMEPQGTLD ITQQDTAKGD QLERISNGPV LTLGGSSVSS IQEASNAATQ 1450 1460 1470 1480 1490 1500 QFSGTDLLNG PLASSLNSDV PQQRPSVVVS PHSTTSVIQG HQIIAVPDSG SKVSHSPALS 1510 1520 1530 1540 1550 1560 SDVRSTNGTA ECKTVKRPAE DTDRETVAGI PNKVGVRIVT ISDPNNAGCS ATMVAVPAGA 1570 1580 1590 1600 1610 1620 DPSTVAKVAI ESAVQQKQQH PPTYVQNVVP QNTPMPPSPA VQVQGQPNSS QPSPFSGSSQ 1630 1640 1650 1660 1670 1680 PGDPMRKPGQ NFMCLWQSCK KWFQTPSQVF YHAATEHGGK DVYPGQCLWE GCEPFQRQRF 1690 1700 1710 1720 1730 1740 SFITHLQDKH CSKDALLAGL KQDEPGQAGS QKSSTKQPTV GGTSSTPRAQ KAIVNHPSAA 1750 1760 1770 1780 LMALRRGSRN LVFRDFTDEK EGPITKHIRL TAALILKNIG KYS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Zipzap/p200 is a novel zinc finger protein contributing to cardiac gene regulation." Zhang X., Azhar G., Zhong Y., Wei J.Y. Biochem. Biophys. Res. Commun. 346:794-801(2006) [PubMed: 16782067] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, INTERACTION WITH SRF, SUBUNIT, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE. Tissue: Heart.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 950-1827 (ISOFORM 1).
[3]	"DNA-binding properties of ARID family proteins." Patsialou A., Wilsker D., Moran E. Nucleic Acids Res. 33:66-80(2005) [PubMed: 15640446] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-1093, DNA-BINDING.
[4]	The German cDNA consortium Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 28-1835 (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 150-1835 (ISOFORM 1). Tissue: Liver.
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 976-1835. Tissue: Testis.
[6]	"Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Kikuno R., Nakayama M., Hirosawa M., Ohara O. DNA Res. 7:273-281(2000) [PubMed: 10997877] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1030-1835. Tissue: Brain.
[7]	"Recent advances in understanding chromatin remodeling by SWI/SNF complexes." Martens J.A., Winston F. Curr. Opin. Genet. Dev. 13:136-142(2003) [PubMed: 12672490] [Abstract] Cited for: REVIEW ON SWI/SNF CHROMATIN REMODELING COMPLEXES.
[8]	"PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes." Yan Z., Cui K., Murray D.M., Ling C., Xue Y., Gerstein A., Parsons R., Zhao K., Wang W. Genes Dev. 19:1662-1667(2005) [PubMed: 15985610] [Abstract] Cited for: IDENTIFICATION IN THE PBAF COMPLEX, MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ096628 mRNA. Translation: AAZ74794.1. AK127872 mRNA. Translation: BAC87171.1. AK027718 mRNA. Translation: BAB55320.1. AY727870 mRNA. Translation: AAU20329.2. Different termination. AL832200 mRNA. Translation: CAD91164.1. BX537879 mRNA. Translation: CAD97878.1. CR749833 mRNA. Translation: CAH18689.1. BC090062 mRNA. Translation: AAH90062.1. AB046777 mRNA. Translation: BAB13383.1.
RefSeq	NP_689854.2.
UniGene	Hs.696080
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q68CP9.
Genome annotation databases
Ensembl	ENSG00000189079. Homo sapiens. [Contig view]
GeneID	196528.
KEGG	hsa:196528.
NMPDR	fig|9606.3.peg.7429.
Organism-specific databases
H-InvDB	HIX0010566.
HGNC	HGNC:18037. ARID2.
MIM	609539. gene.
PharmGKB	PA134916396.
HUGE	Search...
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q68CP9.
Gene expression databases
ArrayExpress	Q68CP9.
Family and domain databases
InterPro	IPR001606. ARID. IPR011991. Wing_hlx_DNA_bd. IPR015880. Znf_C2H2-like. [Graphical view]
Gene3D	G3DSA:1.10.150.60. ARID. 1 hit. G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
Pfam	PF01388. ARID. 1 hit. [Graphical view]
SMART	SM00501. BRIGHT. 1 hit. SM00355. ZnF_C2H2. 2 hits. [Graphical view]
PROSITE	PS51011. ARID. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 1 hit. PS50157. ZINC_FINGER_C2H2_2. False negative. [Graphical view]
ProDom	Q68CP9. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
SOURCE	Search...
ProtoNet	Search...

Entry information

Entry name

ARID2_HUMAN

Accession

Primary (citable) accession number: Q68CP9
Secondary accession number(s): Q15KG9 , Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	August 30, 2005
Last modified:	July 22, 2008
This is version 43 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation proj