Reviewed, UniProtKB/Swiss-Prot Q83ER4 (RL5_COXBU)

Names and origin

Protein names

Recommended name:
    50S ribosomal protein L5

Gene names

Name:	rplE
Ordered Locus Names:	CBU_0250

Organism

Coxiella burnetii [Complete proteome] [HAMAP]

Taxonomic identifier

777 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	182 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs By similarity.
Subunit structure	Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome By similarity.
Sequence similarities	Belongs to the ribosomal protein L5P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	rRNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 182	182	50S ribosomal protein L5

Sequences

	Sequence		Length	Mass (Da)
	Q83ER4-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 1596EB7EEF0367F4	FASTA	182	20,748
	10 20 30 40 50 60 MVELQELYKK TITPALQKEF GFKSVMAVPR LEKITLNMGL GEAVADKKVI ERAMDDMIKI 70 80 90 100 110 120 SGQKPLITYA RKSEAGFKIR AGWPIGCKVT LRRDRMYEFL KRLISIAIPR IRDFRGLSPK 130 140 150 160 170 180 SFDGRGNYSL GIREQIVFPE IQYDKVDAIR GMDITITTTA RTDEEGRALL KAFGFPLKDE SR

References

[1]

"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. , Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F. Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed: 12704232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016828 Genomic DNA. Translation: AAO89808.1.
RefSeq	NP_819294.1.
3D structure databases
HSSP	HSSP built from PDB template 1IQ4 based on UniProtKB P08895.
ModBase	Search...
Genome annotation databases
GeneID	1208131.
GenomeReviews	Gene locus CBU_0250 in contig AE016828_GR.
KEGG	cbu:CBU_0250.
NMPDR	fig|227377.1.peg.238.
TIGR	CBU_0250.
Phylogenomic databases
HOGENOM	Q83ER4.
Enzyme and pathway databases
BioCyc	CBUR227377:CBU_0250-MON.
Family and domain databases
HAMAP	MF_01333. [Tree]
InterPro	IPR002132. Ribosomal_L5. [Graphical view]
Gene3D	G3DSA:3.30.1440.10. Ribosomal_L5. 1 hit.
PANTHER	PTHR11994. Ribosomal_L5. 1 hit.
Pfam	PF00281. Ribosomal_L5. 1 hit. PF00673. Ribosomal_L5_C. 1 hit. [Graphical view]
PIRSF	PIRSF002161. Ribosomal_L5. 1 hit.
ProDom	PD013434. Ribosomal_L5_mit. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00358. RIBOSOMAL_L5. 1 hit. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

RL5_COXBU

Accession

Primary (citable) accession number: Q83ER4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2004
Last sequence update:	June 1, 2003
Last modified:	July 22, 2008
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)