Reviewed, UniProtKB/Swiss-Prot Q83ES3 (RL4_COXBU)

Names and origin

Protein names

Recommended name:
    50S ribosomal protein L4

Gene names

Name:	rplD
Ordered Locus Names:	CBU_0239

Organism

Coxiella burnetii [Complete proteome] [HAMAP]

Taxonomic identifier

777 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	205 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity. Forms part of the polypeptide exit tunnel By similarity.
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L4P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	rRNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 205	205	50S ribosomal protein L4

Sequences

	Sequence		Length	Mass (Da)
	Q83ES3-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 0EF928AB6850122E	FASTA	205	22,374
	10 20 30 40 50 60 MELPVNSFDK KEASTLTVAD SAFGSEYKEG LVHQVVNAYL AGGRAGTKAQ KTRREVSGGG 70 80 90 100 110 120 AKPWRQKGTG RARAGSSRSP LWRSGGVAFA AKPRDFTQKV NRKMYRSAMA SILSELIRRE 130 140 150 160 170 180 QLVVVDSLKL NEPKTRELKE SLKKLNLGNV LIIIDGDDRN INLASRNMVG VSVCDALHVD 190 200 PVSLVAAENI VVTVDAVKRL EERLS

References

[1]

"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. , Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F. Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed: 12704232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016828 Genomic DNA. Translation: AAO89797.1.
RefSeq	NP_819283.1.
3D structure databases
HSSP	HSSP built from PDB template 1DMG based on UniProtKB P38516.
ModBase	Search...
Genome annotation databases
GeneID	1208120.
GenomeReviews	Gene locus CBU_0239 in contig AE016828_GR.
KEGG	cbu:CBU_0239.
NMPDR	fig|227377.1.peg.227.
TIGR	CBU_0239.
Phylogenomic databases
HOGENOM	Q83ES3.
Enzyme and pathway databases
BioCyc	CBUR227377:CBU_0239-MON.
Family and domain databases
HAMAP	MF_01328. [Tree]
InterPro	IPR015498. Ribosomal_L4. IPR002136. Ribosomal_L4/L1e. IPR013005. Ribosomal_L4/L1e_bac-type. [Graphical view]
PANTHER	PTHR10746. Ribos_L4_L1E_bac. 1 hit. PTHR10746:SF2. Ribosomal_L4. 1 hit.
Pfam	PF00573. Ribosomal_L4. 1 hit. [Graphical view]
ProDom	Q83ES3. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

RL4_COXBU

Accession

Primary (citable) accession number: Q83ES3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2004
Last sequence update:	June 1, 2003
Last modified:	July 22, 2008
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)