Reviewed, UniProtKB/Swiss-Prot Q83FD6 (RECF_COXBU)

Names and origin

Protein names

Recommended name:
    DNA replication and repair protein recF

Gene names

Name:	recF
Ordered Locus Names:	CBU_0003

Organism

Coxiella burnetii [Complete proteome] [HAMAP]

Taxonomic identifier

777 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	367 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	The recF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP By similarity.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the recF family.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: HAMAP SOS response Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP single-stranded DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 367	367	DNA replication and repair protein recF
Regions
	Nucleotide binding	41 – 48	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q83FD6-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: D99AA014F2DB5401	FASTA	367	42,267
	10 20 30 40 50 60 MWLCLCAYSR MPYIGSLKVN QFRNLADVDI TPHSQFNFFF GQNGAGKTSI LESIYYLSVG 70 80 90 100 110 120 RSFRTHLPQR LIQDNTDRFL IFITLYNGTQ FIPLGVERDC HGDRCLRING ETASSWSLAA 130 140 150 160 170 180 KRLPLCSLSA MSHRFLLDGP RVRRQFLDWL MFHVEPSFFS IWQRLQRSLK QRNAALKAKL 190 200 210 220 230 240 PLGEITHWDK MLVEDGERLH QLRQNVVTEF KPLFTQMLQQ FLPAYPLIGH YFRGWSEKYS 250 260 270 280 290 300 LMEQLQINLK QDLQRGYTQA GPQRADFRLT LGDLPAQDIL SQGQQKLVTY ALHFAQGLLL 310 320 330 340 350 360 KEKTGISPIY LIDDLPAELD ANKRDCVIDL VNCLESQVFI SGIDPNEIRL PPHSTLFHVK HGKVAAL

References

[1]

"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. , Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F. Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed: 12704232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016828 Genomic DNA. Translation: AAO89573.1.
RefSeq	NP_819059.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1207923.
GenomeReviews	Gene locus CBU_0003 in contig AE016828_GR.
KEGG	cbu:CBU_0003.
NMPDR	fig|227377.1.peg.3.
TIGR	CBU_0003.
Phylogenomic databases
HOGENOM	Q83FD6.
Enzyme and pathway databases
BioCyc	CBUR227377:CBU_0003-MON.
Family and domain databases
HAMAP	MF_00365. [Tree]
InterPro	IPR001238. RecF. IPR003395. RecF/RecN/SMC_N. [Graphical view]
Pfam	PF02463. SMC_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00611. recf. 1 hit.
PROSITE	PS00617. RECF_1. 1 hit. PS00618. RECF_2. 1 hit. [Graphical view]
ProDom	Q83FD6. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

RECF_COXBU

Accession

Primary (citable) accession number: Q83FD6

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2004
Last sequence update:	June 1, 2003
Last modified:	July 22, 2008
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)