Reviewed, UniProtKB/Swiss-Prot Q852M2 (ALDO3_ORYSJ)

Names and origin

Protein names

Recommended name:
    Probable aldehyde oxidase 3
      Short name=AO-3
    EC=1.2.3.1

Gene names

Ordered Locus Names:	Os03g0790700, LOC_Os03g57680
ORF Names:	OSJNBa0087O09.19

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	1356 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	An aldehyde + H(2)O + O(2) = a carboxylic acid + H(2)O(2).
Cofactor	Binds 2 2Fe-2S clusters By similarity. FAD By similarity. Molybdopterin By similarity.
Subunit structure	Aldehyde oxidases (AO) are homo- and heterodimers of AO subunits By similarity.
Sequence similarities	Belongs to the xanthine dehydrogenase family. Contains 1 2Fe-2S ferredoxin-type domain. Contains 1 FAD-binding PCMH-type domain.

Ontologies

Keywords
Biological process	Abscisic acid biosynthesis Auxin biosynthesis
Ligand	2Fe-2S FAD Flavoprotein Iron Iron-sulfur Metal-binding Molybdenum NAD
Molecular function	Oxidoreductase
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 1356	1356	Probable aldehyde oxidase 3
Regions
	Domain	10 – 97	88	2Fe-2S ferredoxin-type
	Domain	245 – 437	193	FAD-binding PCMH-type
Sites
	Metal binding	49	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	54	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	57	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	79	1	Iron-sulfur (2Fe-2S) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q852M2-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 899961AA38FEE51E	FASTA	1,356	145,336
	10 20 30 40 50 60 MGSEAAAAAR AVVVAVNGER YEAVGVDPST TLLEFLRTRT PVRGPKLGCG EGGCGACVVV 70 80 90 100 110 120 VSKYDAVADE VTEFSASSCL TLLGSLHHCA VTTSEGIGNS RDGFHAVQRR LSGFHASQCG 130 140 150 160 170 180 FCTPGMCMSI YSALAKADKA SGRPAPPTGF SKITAAEAEK AVSGNLCRCT GYRPIVDACK 190 200 210 220 230 240 SFAADVDLED LGLNAFWKKG VDDEHADINK LPAYSGGAAV CTFPEFLKSE IRSSMGQANG 250 260 270 280 290 300 DTSAVVVTGD GWFHPKSVEE FHRLFDSNLF DERSVKIVAS NTGSGVYKDQ DLHDKYINIS 310 320 330 340 350 360 QIPELSAINR SSKGVEIGAV VSISQAIDIL SDGGAVFRKI ADHLSKVASP FVRNTATIGG 370 380 390 400 410 420 NIIMAQRLSF SSDIATVLLA AGSTVTIQVA AKRMCITLEE FLKQPPCDSR TLLVSISIPD 430 440 450 460 470 480 WGSDDGITFQ TFRAAPRPLG NAVSYVNSAF LARSSVDGSS GSHLIEDVCL AFGPFGAKHA 490 500 510 520 530 540 IRAREVEKFL KGKLVSAPVI LEAVRLLKGV VSPAEGTTHP EYRVSLAVSY LFKFLSSLTN 550 560 570 580 590 600 GLDEPENANV PNGSFTNGTA NGIVDSSPEK HSNVDSSYLP IKSRQEMVFS DEYRPIGKPI 610 620 630 640 650 660 EKTGAELQAS GEAVYVDDIS APKDCLYGAF IYSTHPHAHI KGVNFRSSLA SQKVITVITL 670 680 690 700 710 720 KDIPTNGKNI GSCSPMLGDE ALFVDPVSEF AGQNIGVVIA ETQKYAYMAA KQSVIEYSTE 730 740 750 760 770 780 NLQPPILTVE DAVQHNSYFQ VPPFLAPTPI GEFNQAMSEA DHKIIDGEVK LESQYYFYME 790 800 810 820 830 840 TQTALAIPDE DNCITLYVSA QLPEITQNTV ARCLGIPYHN VRIITRRVGG GFGGKAMKAI 850 860 870 880 890 900 HVATACAVAA FKLRRPVRMY LDRKTDMIMA GGRHPMKVKY SVGFKSDGKI TGLHVDLRIN 910 920 930 940 950 960 CGISPDCSPA LPVAIVGALK KYNWGALSFD IKLCKTNVSS KSAMRAPGDA QGSFIAEAIV 970 980 990 1000 1010 1020 EHIASTLSVD TNAIRRKNLH DFESLKVFYG NSAGDPSTYS LVTIFDKLAS SPEYQQRAAV 1030 1040 1050 1060 1070 1080 VEHFNAGSRW KKRGISCVPI TYDVRLRPSP GKVSIMNDGS IAVEVGGVEI GQGLWTKVKQ 1090 1100 1110 1120 1130 1140 MTAFALGQLC DDGGEGLLDK VRVIQADTLS MIQGGFTGGS TTSETSCEAV RKSCAALVER 1150 1160 1170 1180 1190 1200 LKPIKEKAGT LPWKSLIAQA SMASVKLTEH AYWTPDPTFT SYLNYGAAIS EVEVDVLTGE 1210 1220 1230 1240 1250 1260 TTILRSDLVY DCGQSLNPAV DLGQVEGAFV QGIGFFTNEE YTTNSDGLVI NDGTWTYKIP 1270 1280 1290 1300 1310 1320 TVDTIPKQFN VELINSARDH KRVLSSKASG EPPLLLASSV HCAMREAIRA ARKEFAGAGG 1330 1340 1350 SSLTFQMDVP ATMPIVKELC GLDVVERDLE SFAAKA

References

[1]

"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species." The rice chromosome 3 sequencing consortium Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H.-I., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S. Genome Res. 15:1284-1291(2005) [PubMed: 16109971] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC087096 Genomic DNA. Translation: AAO24918.1.
RefSeq	NP_001051517.1.
UniGene	Os.88638
3D structure databases
HSSP	HSSP built from PDB template 1FO4 based on UniProtKB P80457.
ModBase	Search...
Genome annotation databases
GeneID	4334381.
KEGG	osa:4334381.
Organism-specific databases
Gramene	Q852M2.
Family and domain databases
InterPro	IPR002888. 2Fe-2S_bd. IPR006058. 2Fe2S_fd_BS. IPR000674. Ald_Oxase/Xan_DHase_a/b. IPR016208. Ald_Oxase/xanthine_DHase. IPR008274. AldOxase/xan_DHase_Mopterin-bd. IPR005107. CO_DHase_flav_C. IPR016169. CO_DHase_flavot_FAD-bd_sub2. IPR001041. Ferredoxin. IPR002346. Mopterin_DHase_FAD-bd. [Graphical view]
Gene3D	G3DSA:3.30.365.10. Ald_xan_DH_mo_bd. 2 hits. G3DSA:3.90.1170.50. Aldxan_DH_hamm. 1 hit. G3DSA:3.30.390.50. CO_DH_flav_C. 1 hit. G3DSA:3.30.465.10. CO_DH_flavoprot_FAD-bd_sub2. 1 hit.
Pfam	PF01315. Ald_Xan_dh_C. 1 hit. PF02738. Ald_Xan_dh_C2. 1 hit. PF03450. CO_deh_flav_C. 1 hit. PF00941. FAD_binding_5. 1 hit. PF00111. Fer2. 1 hit. PF01799. Fer2_2. 1 hit. [Graphical view]
PIRSF	PIRSF000127. Xanthine_DH. 1 hit.
ProDom	PD186071. 2Fe-2S_bind. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00197. 2FE2S_FER_1. 1 hit. PS51085. 2FE2S_FER_2. 1 hit. PS51387. FAD_PCMH. 1 hit. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

ALDO3_ORYSJ

Accession

Primary (citable) accession number: Q852M2

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2006
Last sequence update:	June 1, 2003
Last modified:	September 2, 2008
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)