Skip Header

 
Contribute Send feedback

Reviewed, UniProtKB/Swiss-Prot Q8CHG5 (K0317_MOUSE)

Last modified July 22, 2008. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Protein KIAA0317
Gene names
Name: Kiaa0317
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Hide | Top

Protein attributes

Sequence length823 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

Hide | Top

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane proteinPotential.

Sequence similarities

Contains 1 filamin repeat.

Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.

Hide | Top

Ontologies

Keywords

   Biological processUbl conjugation pathway
   Cellular componentMembrane
   DomainTransmembrane

Gene Ontology (GO)

None. [Check GOA]

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical view

Molecule processing

Chain1 – 823823Protein KIAA0317

Regions

Transmembrane2 – 2221 Potential
Repeat64 – 15895Filamin
Domain483 – 823341HECT

Experimental info

Sequence conflict4241T → I in AAH60658. Ref.3

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
Q8CHG5-1 [UniParc].

Last modified March 29, 2005. Version 2.
Checksum: E74AAE76555A20D4

FASTA82394,199
        10         20         30         40         50         60 
MFYVIGGIIV SVVAFFFTIK FLFELAARVV SFLQNEDRER RGDRTIYDYV RGNYLDPRSC 

        70         80         90        100        110        120 
KVSWDWKDPY EVGHSMAFRV HLFYKNGQPF PAHRPVGLRV HISHVELAVD IPVTQEVLQE 

       130        140        150        160        170        180 
PNSNVVKVAF TVRKAGRYEI TVKLGGLNVA YSPYYKIFQP GMVVPSKTKI VCHFSTLVLT 

       190        200        210        220        230        240 
CGQPHTLQIV PRDEYDNPTN NSMSLRDEHS YSLAIHELGP QEEENNEVSF EKSVTSNRQT 

       250        260        270        280        290        300 
CQVFLRLTLH SRGCFHACIS YQNQPINNGE FDIIVLSENE KNIVERNVST SGVSIYFEAY 

       310        320        330        340        350        360 
LYNANNCTST PWHLPPMHMS SSQRRPSTAI EEDDEDSPSE CHTPEKVKKP KKVYCYVSPK 

       370        380        390        400        410        420 
QFSVKEFYLK IIPWRLYTFR VCPGTKFSYL GPDPVHKLLT LVVDDGIQPP VELSCKERNI 

       430        440        450        460        470        480 
LAATFIRSLH KNIGGSETFQ DKVNFFQREL RQVHMKRPHS KVTLKVSRHA LLESSLKATR 

       490        500        510        520        530        540 
NFSISDWSKN FEVVFQDEEA LDWGGPRREW FELICKALFD TTSQLFARFT DSNQALVHPN 

       550        560        570        580        590        600 
PNRPAHLRLK MYEFAGRLVG KCLYESSLGG AYKQLVRARF TRSFLAQIIG LRMHYKYFET 

       610        620        630        640        650        660 
DDPEFYKSKV CFILNNDMSE MELVFAEEKY NKSGQLDKIV ELMTGGAQTP VTNANKIFYL 

       670        680        690        700        710        720 
NLLAQYRLAS QVKEEVEHFL KGLNELVPEN LLAIFDENEL ELLMCGTGDI NVSDFKAHAV 

       730        740        750        760        770        780 
VVGGSWHFRE KVMRWFWAVV SSLTQEELAR LLQFTTGSSQ LPPGGFAALC PSFQIIAAPT 

       790        800        810        820 
HSTLPTAHTC FNQLCLPTYD SYEEVHRMLQ LAISEGCEGF GML

« Hide

Hide | Top

References

[1]"Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N., Kikuno R., Ohara R., Inamoto S., Hara Y., Nagase T., Ohara O., Koga H.
DNA Res. 9:179-188(2002) [PubMed: 12465718] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Testis.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6.
Tissue: Brain and Eye.

Hide | Top

Cross-references

Sequence databases

AB093230 mRNA. Translation: BAC41414.1. Different initiation.
AK077015 mRNA. Translation: BAC36566.1.
BC049900 mRNA. Translation: AAH49900.1.
BC060658 mRNA. Translation: AAH60658.1.
RefSeqNP_835166.2.
UniGeneMm.24446

3D structure databases

HSSPHSSP built from PDB template 1ND7 based on UniProtKB Q9H0M0.
ModBaseSearch...

PTM databases

PhosphoSiteQ8CHG5.

Genome annotation databases

EnsemblENSMUSG00000042350. Mus musculus. [Contig view]
GeneID68497.
KEGGmmu:68497.

Organism-specific databases

MGIMGI:1915747. 1110018G07Rik.
RougeSearch...

Phylogenomic databases

HOGENOMQ8CHG5.
HOVERGENQ8CHG5.

Gene expression databases

ArrayExpressQ8CHG5.
CleanExMM_1110018G07RIK.
GermOnlineENSMUSG00000042350. Mus musculus.

Family and domain databases

InterProIPR001298. Filamin.
IPR000569. HECT.
[Graphical view]
PfamPF00630. Filamin. 1 hit.
PF00632. HECT. 1 hit.
[Graphical view]
SMARTSM00119. HECTc. 1 hit.
SM00557. IG_FLMN. 1 hit.
[Graphical view]
PROSITEPS50194. FILAMIN_REPEAT. 1 hit.
PS50237. HECT. 1 hit.
[Graphical view]
ProDomQ8CHG5.
[Graphical view] [Entries sharing at least one domain]
BLOCKSSearch...

Other Resources

SOURCESearch...
ProtoNetSearch...

Hide | Top

Entry information

Entry nameK0317_MOUSE
AccessionPrimary (citable) accession number: Q8CHG5
Secondary accession number(s): Q6P9Q1, Q80YC4, Q8C5W5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: March 29, 2005
Last modified: July 22, 2008
This is version 43 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

Hide | Top

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB secondary accession numbers

Index of UniProtKB secondary accession numbers

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents