Reviewed, UniProtKB/Swiss-Prot Q8K2B0 (SC65_MOUSE)

Names and origin

Protein names

Recommended name:
    Synaptonemal complex protein SC65

Gene names

Name:

Sc65

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	443 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Nucleus › nucleolusBy similarity.
Sequence similarities	Belongs to the CRTAP/No55 family.

Ontologies

Keywords
Cellular component	Nucleus
PTM	Phosphoprotein
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 443	443	Synaptonemal complex protein SC65
Regions
	Compositional bias	352 – 443	92	Asp/Glu-rich (acidic)
Amino acid modifications
	Modified residue	240	1	Phosphotyrosine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8K2B0-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 99FA2B03344F15B1	FASTA	443	51,132
	10 20 30 40 50 60 MARGAWGLLW LLLGSAGAQY EKYSFRGFPP EDLMPLATAY GHALEQYEGE SWRESARYLE 70 80 90 100 110 120 AALRLHRLLR DSEAFCHANC SGPATSQPRP ASGPDGDHDG DGEDWARELR LFGHVLERAA 130 140 150 160 170 180 CLRRCKKTLP AFQVPYPPRQ LLRDFQSRLP YQYLHYAHFK ANRLEKAVAA AYTFLQRNPK 190 200 210 220 230 240 HELTAKYLNY YRGMLDIGDE SLTDLEAQPY EAVFLRAVKL YNSGDFRSST EDMERALAEY 250 260 270 280 290 300 MTVFARCLAG CEGAHEQVDF KDFYPAIADL FAESLQCKVD CETNLTPNVG GFFVDKFVAT 310 320 330 340 350 360 MYHYLQFAYY KLNDVRQAAR SAASYMLFDP KDSVMQQNLV YYRFHRARWG LEDEDFQPRE 370 380 390 400 410 420 EAMLYHNQTS ELRELLDFTH MYLQSDDEME LEETESLPEP EEPLSDAEFE GEGDYEEGLY 430 440 ADWWQEPEAK GDEAEAEPEP ELT

References

[1]	The mouse genome sequencing consortium Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: FVB/N. Tissue: Mammary tumor.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL590968 Genomic DNA. Translation: CAM23031.1. BC031856 mRNA. Translation: AAH31856.1.
RefSeq	NP_789800.1.
UniGene	Mm.4940
3D structure databases
ModBase	Search...
PTM databases
PhosphoSite	Q8K2B0.
Genome annotation databases
Ensembl	ENSMUSG00000006931. Mus musculus. [Contig view]
GeneID	66180.
KEGG	mmu:66180.
Organism-specific databases
MGI	MGI:1913430. 1110036O03Rik.
Phylogenomic databases
HOGENOM	Q8K2B0.
HOVERGEN	Q8K2B0.
Gene expression databases
ArrayExpress	Q8K2B0.
CleanEx	MM_1110036O03RIK.
Family and domain databases
ProDom	Q8K2B0. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
SOURCE	Search...
ProtoNet	Search...

Entry information

Entry name

SC65_MOUSE

Accession

Primary (citable) accession number: Q8K2B0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	October 1, 2002
Last modified:	July 22, 2008
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)