Reviewed, UniProtKB/Swiss-Prot Q8NFR3 (ADMP_HUMAN)

Names and origin

Protein names

Recommended name:
    Protein ADMP

Gene names

Name:	ADMP
Synonyms:	C3orf57

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	76 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	May play a possible role in signal transduction.
Subcellular location	Membrane; Single-pass membrane proteinPotential.
Tissue specificity	Expression is seen predominantly in the prostate epithelium with weaker expression in the fibroblasts and endothelial cells.
Induction	Expression is suppressed by androgens in the androgen-sensitive LNCaP cell line.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 76	76	Protein ADMP
Regions
	Transmembrane	37 – 57	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8NFR3-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: F43280DBC07B5A0E	FASTA	76	9,198
	10 20 30 40 50 60 MDLRRVKEYF SWLYYQYQII SCCAVLEPWE RSMFNTILLT IIAMVVYTAY VFIPIHIRLA 70 WEFFSKICGY HSTISN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Zan Q., Guo J.H., Yu L. Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung and Mammary gland.
[3]	"Molecular cloning and characterization of a novel androgen repressible gene expressed in the prostate epithelium." Singh J., Young L., Handelsman D.J., Dong Q. Gene 348:55-63(2005) [PubMed: 15777716] [Abstract] Cited for: INDUCTION, TISSUE SPECIFICITY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF458592 mRNA. Translation: AAM49720.1. BC065208 mRNA. Translation: AAH65208.1. BC071875 mRNA. Translation: AAH71875.1. BC107756 mRNA. Translation: AAI07757.1.
RefSeq	NP_001035189.1.
UniGene	Hs.369104
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000196542. Homo sapiens. [Contig view]
GeneID	165679.
KEGG	hsa:165679.
Organism-specific databases
HGNC	HGNC:24045. C3orf57.
MIM	610412. gene.
GenAtlas	Search...
GeneCards	Search...
GeneLynx	Search...
Phylogenomic databases
HOGENOM	Q8NFR3.
HOVERGEN	Q8NFR3.
Gene expression databases
CleanEx	HS_C3orf57.
GermOnline	ENSG00000196542. Homo sapiens.
Family and domain databases
ProDom	Q8NFR3. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
SOURCE	Search...
ProtoNet	Search...

Entry information

Entry name

ADMP_HUMAN

Accession

Primary (citable) accession number: Q8NFR3
Secondary accession number(s): Q0P5S6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 13, 2006
Last sequence update:	October 1, 2002
Last modified:	July 22, 2008
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)