AT-hook-containing transcription factor 1

Names and origin

Protein names

Recommended name:
AT-hook-containing transcription factor 1
Alternative name(s):
Embryonic large molecule derived from yolk sac

Gene names

Name:	AHCTF1
Synonyms:	ELYS, TMBS62
ORF Names:	MSTP108

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length	2275 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

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General annotation (Comments)

Function	Probable transcription factor which may play a specific role in hematopoietic tissues. May play a role in early development being critical for the survival of inner cells of the blastocyst By similarity.
Subcellular location	Nucleus matrix. CytoplasmBy similarity.
Post-translational modification	Phosphorylated upon DNA damage, probably by ATM or ATR.
Sequence similarities	Contains 1 A.T hook DNA-binding domain.
Sequence caution	AAN65622.1 sequence differs from that shown. Reason: Frameshift at several positions.

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Ontologies

Keywords
Biological process	Transcription
Cellular component	Cytoplasm Nucleus
Coding sequence diversity	Alternative splicing Polymorphism
Ligand	DNA-binding
Molecular function	Developmental protein
PTM	Phosphoprotein
Gene Ontology (GO)
Cellular component	nuclear matrix Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

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Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8WYP5-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8WYP5-2) The sequence of this isoform differs from the canonical sequence as follows: 1-7: MAAERRC → MDSLAGLSPREAAGVLSLSCVGVCSTCAWAWPHGSM

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Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Molecule processing

Chain

1 – 2275

2275

AT-hook-containing transcription factor 1

Regions

DNA binding

1955 – 1967

13

A.T hook

Region

10 – 990

981

Necessary for cytoplasmic localization By similarity

Region

1158 – 2275

1118

Necessary for nuclear localization By similarity

Region

1455 – 1707

253

Mediates transcriptional activity By similarity

Amino acid modifications

Modified residue

537

1

Phosphoserine

Modified residue

1096

1

Phosphoserine

Modified residue

1225

1

Phosphoserine

Modified residue

1227

1

Phosphoserine

Modified residue

1231

1

Phosphoserine

Modified residue

1241

1

Phosphoserine

Modified residue

1292

1

Phosphoserine

Modified residue

1304

1

Phosphoserine

Modified residue

1522

1

Phosphoserine

Modified residue

1550

1

Phosphoserine

Modified residue

1817

1

Phosphothreonine

Modified residue

1953

1

Phosphoserine

Modified residue

2005

1

Phosphoserine

Modified residue

2221

1

Phosphoserine

Modified residue

2231

1

Phosphoserine

Modified residue

2235

1

Phosphoserine

Natural variations

Alternative sequence

1 – 7

7

MAAERRC → MDSLAGLSPREAAGVLSLSC VGVCSTCAWAWPHGSM in isoform 2.

Natural variant

883

1

N → S: dbSNP rs2642990.

Natural variant

2194

1

L → V: dbSNP rs12410563.

Experimental info

Sequence conflict

177

1

V → I in BAB78516. Ref.1

Sequence conflict

216

1

Q → E in BAB78516. Ref.1

Sequence conflict

246

1

V → A in BAB78516. Ref.1

Sequence conflict

288

1

P → R in BAB78516. Ref.1

Sequence conflict

412

1

D → G in AAN65622. Ref.2

Sequence conflict

655

1

T → A in BAB78516. Ref.1

Sequence conflict

752

1

D → G in AAN65622. Ref.2

Sequence conflict

762

1

A → G in AAN65622. Ref.2

Sequence conflict

1143

1

F → S in AAN65622. Ref.2

Sequence conflict

1216

1

L → P in BAB78516. Ref.1

Sequence conflict

1279

1

L → P in BAB78516. Ref.1

Sequence conflict

1746

1

S → F in CAB45737. Ref.3

Sequence conflict

1806

1

S → F in BAB78516. Ref.1

Sequence conflict

1839

1

E → G in AAN65622. Ref.2

Sequence conflict

2137

1

K → E in AAN65622. Ref.2

Sequence conflict

2196

1

K → E in AAH12307. Ref.5

Sequence conflict

2222

1

P → L in BAB78516. Ref.1

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Sequences

Sequence		Length	Mass (Da)
Isoform 1 [UniParc]. Last modified July 25, 2006. Version 2. Checksum: 5C8BB4E793190599 Show »	FASTA	2,275	253,460
10 20 30 40 50 60 MAAERRCGSM RDLRAQVTSG LLPFPEVTLQ ALGEDEITLE SVLRGKFAAG KNGLACLACG 70 80 90 100 110 120 PQLEVVNSIT GERLSAYRFS GVNEQPPVVL AVKEFSWQKR TGLLIGLEET EGSVLCLYDL 130 140 150 160 170 180 GISKVVKAVV LPGRVTAIEP IINHGGASAS TQHLHPSLRW LFGVAAVVTD VGQILLVDLC 190 200 210 220 230 240 LDDLSCNQNE VEASDLEVLT GIPAEVPHIR ESVMRQGRHL CFQLVSPTGT AVSTLSYISR 250 260 270 280 290 300 TNQLAVGFSD GYLALWNMKS MKREYYIQLE SGQVPVYAVT FQEPENDPRN CCYLWAVQST 310 320 330 340 350 360 QDSEGDVLSL HLLQLAFGNR KCLASGQILY EGLEYCEERY TLDLTGGMFP LRGQTSNTKL 370 380 390 400 410 420 LGCQSIEKFR SHGDREEGVN EALSPDTSVS VFTWQVNIYG QGKPSVYLGL FDINRWYHAQ 430 440 450 460 470 480 MPDSLRSGEY LHNCSYFALW SLESVVSRTS PHGILDILVH ERSLNRGVPP SYPPPEQFFN 490 500 510 520 530 540 PSTYNFDATC LLNSGVVHLT CTGFQKETLT FLKKSGPSLN ELIPDGYNRC LVAGLLSPRF 550 560 570 580 590 600 VDVQPSSLSQ EEQLEAILSA AIQTSSLGLL TGYIRRWITE EQPNSATNLR FVLEWTWNKV 610 620 630 640 650 660 VLTKEEFDRL CVPLFDGSCH FMDPQTIQSI QQCYLLLSNL NIVLSCFASE AREITERGLI 670 680 690 700 710 720 DLSNKFVVSH LICQYAQVVL WFSHSGLLPE GIDDSVQLSR LCYNYPVIQN YYTSRRQKFE 730 740 750 760 770 780 RLSRGKWNPD CLMIDGLVSQ LGERIEKLWK RDEGGTGKYP PASLHAVLDM YLLDGVTEAA 790 800 810 820 830 840 KHSITIYLLL DIMYSFPNKT DTPIESFPTV FAISWGQVKL IQGFWLIDHN DYESGLDLLF 850 860 870 880 890 900 HPATAKPLSW QHSKIIQAFM SQGEHRQALR YIQTMKPTVS SGNDVILHLT VLLFNRCMVE 910 920 930 940 950 960 AWNFLRQHCN RLNIEELLKH MYEVCQEMGL MEDLLKLPFT DTEQECLVKF LQSSASVQNH 970 980 990 1000 1010 1020 EFLLVHHLQR ANYVPALKLN QTLKINVMND RDPRLRERSL ARNSILDQYG KILPRVHRKL 1030 1040 1050 1060 1070 1080 AIERAKPYHL STSSVFRLVS RPKPLSAVPK QVVTGTVLTR SVFINNVLSK IGEVWASKEP 1090 1100 1110 1120 1130 1140 INSTTPFNSS KIEEPSPIVY SLPAPELPEA FFGTPISKAS QKISRLLDLV VQPVPRPSQC 1150 1160 1170 1180 1190 1200 SEFIQQSSMK SPLYLVSRSL PSSSQLKGSP QAISRASELH LLETPLVVKK AKSLAMSVTT 1210 1220 1230 1240 1250 1260 SGFSEFTPQS ILRSTLRSTP LASPSPSPGR SPQRLKETRI SFVEEDVHPK WIPGAADDSK 1270 1280 1290 1300 1310 1320 LEVFTTPKKC AVPVETEWLK SKDRTTSFFL NSPEKEHQEM DEGSQSLEKL DVSKGNSSVS 1330 1340 1350 1360 1370 1380 ITSDETTLEY QDAPSPEDLE ETVFTASKPK SSSTALTTNV TEQTEKDGDK DVFASEVTPS 1390 1400 1410 1420 1430 1440 DLQKQMGNLE DAETKDLLVA AEAFSELNHL SPVQGTEASL CAPSVYEGKI FTQKSKVPVL 1450 1460 1470 1480 1490 1500 DEGLTSVETY TPAIRANDNK SMADVLGDGG NSSLTISEGP IVSERRLNQE VALNLKEDHE 1510 1520 1530 1540 1550 1560 VEVGVLKESV DLPEEKLPIS DSPPDTQEIH VIEQEKLEAQ DSGEEARNLS FNELYPSGTL 1570 1580 1590 1600 1610 1620 KLQYNFDTID QQFCDLADNK DTAECDIAEV DGELFVAQSN FTLILEGEEG EVEPGDFASS 1630 1640 1650 1660 1670 1680 DVLPKAANTA TEEKLVCSGE NDNHGQIANL PSAVTSDQKS QKVDTLPYVP EPIKVAIAEN 1690 1700 1710 1720 1730 1740 LLDVIKDTRS KEITSDTMEQ SIHETIPLVS QNIMCPTKLV KSAFKTAQET STMTMNVSQV 1750 1760 1770 1780 1790 1800 DDVVSSKTRT RGQRIQNVNV KSAQQEASAD VATPKMPGQS VRKKTRKAKE ISEASENIYS 1810 1820 1830 1840 1850 1860 DVRGLSQNQQ IPQNSVTPRR GRRKKEVNQD ILENTSSVEQ ELQITTGRES KRLKSSQLLE 1870 1880 1890 1900 1910 1920 PAVEETTKKE VKVSSVTKRT PRRIKRSVEN QESVEIINDL KVSTVTSPSR MIRKLRSTNL 1930 1940 1950 1960 1970 1980 DASENTGNKQ DDKSSDKQLR IKHVRRVRGR EVSPSDVRED SNLESSQLTV QAEFDMSAIP 1990 2000 2010 2020 2030 2040 RKRGRPRKIN PSEDVGSKAV KEERSPKKKE APSIRRRSTR NTPAKSENVD VGKPALGKSI 2050 2060 2070 2080 2090 2100 LVPNEELSMV MSSKKKLTKK TESQSQKRSL HSVSEERTDE MTHKETNEQE ERLLATASFT 2110 2120 2130 2140 2150 2160 KSSRSSRTRS SKAILLPDLS EPNNEPLFSP ASEVPRKAKA KKIEVPAQLK ELVSDLSSQF 2170 2180 2190 2200 2210 2220 VISPPALRSR QKNTSNKNKL EDELKDDAQS VETLGKPKAK RIRTSKTKQA SKNTEKESAW 2230 2240 2250 2260 2270 SPPPIEIRLI SPLASPADGV KSKPRKTTEV TGTGLGRNRK KLSSYPKQIL RRKML « Hide
Isoform 2 [UniParc]. Checksum: FBF034AC57CA4287 Show »		2,304	256,276
10 20 30 40 50 60 MDSLAGLSPR EAAGVLSLSC VGVCSTCAWA WPHGSMGSMR DLRAQVTSGL LPFPEVTLQA 70 80 90 100 110 120 LGEDEITLES VLRGKFAAGK NGLACLACGP QLEVVNSITG ERLSAYRFSG VNEQPPVVLA 130 140 150 160 170 180 VKEFSWQKRT GLLIGLEETE GSVLCLYDLG ISKVVKAVVL PGRVTAIEPI INHGGASAST 190 200 210 220 230 240 QHLHPSLRWL FGVAAVVTDV GQILLVDLCL DDLSCNQNEV EASDLEVLTG IPAEVPHIRE 250 260 270 280 290 300 SVMRQGRHLC FQLVSPTGTA VSTLSYISRT NQLAVGFSDG YLALWNMKSM KREYYIQLES 310 320 330 340 350 360 GQVPVYAVTF QEPENDPRNC CYLWAVQSTQ DSEGDVLSLH LLQLAFGNRK CLASGQILYE 370 380 390 400 410 420 GLEYCEERYT LDLTGGMFPL RGQTSNTKLL GCQSIEKFRS HGDREEGVNE ALSPDTSVSV 430 440 450 460 470 480 FTWQVNIYGQ GKPSVYLGLF DINRWYHAQM PDSLRSGEYL HNCSYFALWS LESVVSRTSP 490 500 510 520 530 540 HGILDILVHE RSLNRGVPPS YPPPEQFFNP STYNFDATCL LNSGVVHLTC TGFQKETLTF 550 560 570 580 590 600 LKKSGPSLNE LIPDGYNRCL VAGLLSPRFV DVQPSSLSQE EQLEAILSAA IQTSSLGLLT 610 620 630 640 650 660 GYIRRWITEE QPNSATNLRF VLEWTWNKVV LTKEEFDRLC VPLFDGSCHF MDPQTIQSIQ 670 680 690 700 710 720 QCYLLLSNLN IVLSCFASEA REITERGLID LSNKFVVSHL ICQYAQVVLW FSHSGLLPEG 730 740 750 760 770 780 IDDSVQLSRL CYNYPVIQNY YTSRRQKFER LSRGKWNPDC LMIDGLVSQL GERIEKLWKR 790 800 810 820 830 840 DEGGTGKYPP ASLHAVLDMY LLDGVTEAAK HSITIYLLLD IMYSFPNKTD TPIESFPTVF 850 860 870 880 890 900 AISWGQVKLI QGFWLIDHND YESGLDLLFH PATAKPLSWQ HSKIIQAFMS QGEHRQALRY 910 920 930 940 950 960 IQTMKPTVSS GNDVILHLTV LLFNRCMVEA WNFLRQHCNR LNIEELLKHM YEVCQEMGLM 970 980 990 1000 1010 1020 EDLLKLPFTD TEQECLVKFL QSSASVQNHE FLLVHHLQRA NYVPALKLNQ TLKINVMNDR 1030 1040 1050 1060 1070 1080 DPRLRERSLA RNSILDQYGK ILPRVHRKLA IERAKPYHLS TSSVFRLVSR PKPLSAVPKQ 1090 1100 1110 1120 1130 1140 VVTGTVLTRS VFINNVLSKI GEVWASKEPI NSTTPFNSSK IEEPSPIVYS LPAPELPEAF 1150 1160 1170 1180 1190 1200 FGTPISKASQ KISRLLDLVV QPVPRPSQCS EFIQQSSMKS PLYLVSRSLP SSSQLKGSPQ 1210 1220 1230 1240 1250 1260 AISRASELHL LETPLVVKKA KSLAMSVTTS GFSEFTPQSI LRSTLRSTPL ASPSPSPGRS 1270 1280 1290 1300 1310 1320 PQRLKETRIS FVEEDVHPKW IPGAADDSKL EVFTTPKKCA VPVETEWLKS KDRTTSFFLN 1330 1340 1350 1360 1370 1380 SPEKEHQEMD EGSQSLEKLD VSKGNSSVSI TSDETTLEYQ DAPSPEDLEE TVFTASKPKS 1390 1400 1410 1420 1430 1440 SSTALTTNVT EQTEKDGDKD VFASEVTPSD LQKQMGNLED AETKDLLVAA EAFSELNHLS 1450 1460 1470 1480 1490 1500 PVQGTEASLC APSVYEGKIF TQKSKVPVLD EGLTSVETYT PAIRANDNKS MADVLGDGGN 1510 1520 1530 1540 1550 1560 SSLTISEGPI VSERRLNQEV ALNLKEDHEV EVGVLKESVD LPEEKLPISD SPPDTQEIHV 1570 1580 1590 1600 1610 1620 IEQEKLEAQD SGEEARNLSF NELYPSGTLK LQYNFDTIDQ QFCDLADNKD TAECDIAEVD 1630 1640 1650 1660 1670 1680 GELFVAQSNF TLILEGEEGE VEPGDFASSD VLPKAANTAT EEKLVCSGEN DNHGQIANLP 1690 1700 1710 1720 1730 1740 SAVTSDQKSQ KVDTLPYVPE PIKVAIAENL LDVIKDTRSK EITSDTMEQS IHETIPLVSQ 1750 1760 1770 1780 1790 1800 NIMCPTKLVK SAFKTAQETS TMTMNVSQVD DVVSSKTRTR GQRIQNVNVK SAQQEASADV 1810 1820 1830 1840 1850 1860 ATPKMPGQSV RKKTRKAKEI SEASENIYSD VRGLSQNQQI PQNSVTPRRG RRKKEVNQDI 1870 1880 1890 1900 1910 1920 LENTSSVEQE LQITTGRESK RLKSSQLLEP AVEETTKKEV KVSSVTKRTP RRIKRSVENQ 1930 1940 1950 1960 1970 1980 ESVEIINDLK VSTVTSPSRM IRKLRSTNLD ASENTGNKQD DKSSDKQLRI KHVRRVRGRE 1990 2000 2010 2020 2030 2040 VSPSDVREDS NLESSQLTVQ AEFDMSAIPR KRGRPRKINP SEDVGSKAVK EERSPKKKEA 2050 2060 2070 2080 2090 2100 PSIRRRSTRN TPAKSENVDV GKPALGKSIL VPNEELSMVM SSKKKLTKKT ESQSQKRSLH 2110 2120 2130 2140 2150 2160 SVSEERTDEM THKETNEQEE RLLATASFTK SSRSSRTRSS KAILLPDLSE PNNEPLFSPA 2170 2180 2190 2200 2210 2220 SEVPRKAKAK KIEVPAQLKE LVSDLSSQFV ISPPALRSRQ KNTSNKNKLE DELKDDAQSV 2230 2240 2250 2260 2270 2280 ETLGKPKAKR IRTSKTKQAS KNTEKESAWS PPPIEIRLIS PLASPADGVK SKPRKTTEVT 2290 2300 GTGLGRNRKK LSSYPKQILR RKML « Hide

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References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues." Kimura N., Takizawa M., Okita K., Natori O., Igarashi K., Ueno M., Nakashima K., Nobuhisa I., Taga T. Genes Cells 7:435-446(2002) [PubMed: 11952839] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). Tissue: Fetal liver.
[2]	"Cloning of a cDNA that provides partial correction of mitomycin C sensitivity in Fanconi anemia FA-D1 cells." Lightfoot J., Alon N., Buchwald M. Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2). Tissue: Lymphoblast.
[3]	The German cDNA consortium Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1531-2275 (ISOFORMS 1/2). Tissue: Testis.
[4]	Liu B., Zhao B., Wang X.Y., Liu Y.Q., Sheng H., Qin B.M., Zhang Q., Zheng W.Y., Xu H.S., Liu B.H., Lu H., Gong Q., Hui R.T. Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1753-2275 (ISOFORMS 1/2). Tissue: Heart.
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2037-2275 (ISOFORMS 1/2). Tissue: Retinoblastoma.
[6]	"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed: 17081983] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1241; SER-1292; SER-1522; SER-1550; SER-2005; SER-2231 AND SER-2235, MASS SPECTROMETRY. Tissue: Epithelium.
[7]	"A probability-based approach for high-throughput protein phosphorylation analysis and site localization." Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P. Nat. Biotechnol. 24:1285-1292(2006) [PubMed: 16964243] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2231 AND SER-2235, MASS SPECTROMETRY. Tissue: Epithelium.
[8]	"Phosphoproteome analysis of the human mitotic spindle." Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R. Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006) [PubMed: 16565220] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-537; SER-1096; SER-1241; SER-1292; SER-1522; SER-1550; SER-2221 AND SER-2231, MASS SPECTROMETRY. Tissue: Epithelium.
[9]	"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J. Science 316:1160-1166(2007) [PubMed: 17525332] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1292 AND SER-1304, MASS SPECTROMETRY.
[10]	"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis." Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III J. Proteome Res. 7:1346-1351(2008) [PubMed: 18220336] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-537; SER-1225; SER-1227; SER-1231; THR-1817 AND SER-1953, MASS SPECTROMETRY.

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Cross-references

Sequence databases
	AB059277 mRNA. Translation: BAB78516.1. Different initiation. AY157619 mRNA. Translation: AAN65622.1. Frameshift. AL080144 mRNA. Translation: CAB45737.1. AF173978 mRNA. Translation: AAQ13621.1. Different initiation. BC012307 mRNA. Translation: AAH12307.1.
PIR	T12528.
RefSeq	NP_056261.3.
UniGene	Hs.300887
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8WYP5.
PTM databases
PhosphoSite	Q8WYP5.
Genome annotation databases
Ensembl	ENSG00000153207. Homo sapiens. [Contig view]
GeneID	25909.
KEGG	hsa:25909.
Organism-specific databases
H-InvDB	HIX0002544.
HGNC	HGNC:24618. AHCTF1.
MIM	610853. gene.
PharmGKB	PA142672631.
GenAtlas	Search...
GeneCards	Search...
GeneLynx	Search...
Phylogenomic databases
HOVERGEN	Q8WYP5.
Gene expression databases
ArrayExpress	Q8WYP5.
CleanEx	HS_AHCTF1.
GermOnline	ENSG00000153207. Homo sapiens.
Family and domain databases
InterPro	IPR000637. AT_hook_DNA_bd. [Graphical view]
Pfam	PF02178. AT_hook. 1 hit. [Graphical view]
SMART	SM00384. AT_hook. 1 hit. [Graphical view]
ProDom	Q8WYP5. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
SOURCE	Search...
ProtoNet	Search...

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Entry information

Entry name

AHTF1_HUMAN

Accession

Primary (citable) accession number: Q8WYP5
Secondary accession number(s): Q7Z4E3

Q9Y4Q6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2006
Last sequence update:	July 25, 2006
Last modified:	July 22, 2008
This is version 46 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

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Relevant documents

Human chromosome 1

Human chromosome 1: entries, gene names and cross-references to MIM

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

UniProtKB secondary accession numbers

Index of UniProtKB secondary accession numbers

SIMILARITY comments

Index of protein domains and families

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Keywords

Gene Ontology (GO)

Alternative products

Sequence annotation (Features)

Molecule processing

Regions

Amino acid modifications

Natural variations

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other Resources

Entry information

Relevant documents