Reviewed, UniProtKB/Swiss-Prot Q98924 (HXA9_CHICK)

Names and origin

Protein names

Recommended name:
    Homeobox protein Hox-A9

Gene names

Name:

HOXA9

Organism

Gallus gallus (Chicken)

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	169 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location	Nucleus.
Sequence similarities	Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Homeobox
Ligand	DNA-binding
Molecular function	Developmental protein
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	‹1 – 169	›169	Homeobox protein Hox-A9
Regions
	DNA binding	103 – 162	60	Homeobox
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	Q98924-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 9D74877543924B87	FASTA	169	19,668
	10 20 30 40 50 60 DGRYMRSWLE PVPGSLSFPG LPTSRHYGIK PEPLAARRGD CTTFDTHTLS LSDLPCGSPP 70 80 90 100 110 120 VDRDKQSHEG AFSENNGESE ANGEKPHIDP NNPAANWLHA RSTRKKRCPY TKHQTLELEK 130 140 150 160 EFLFNMYLTR DRRYEVARLL NLTERQVKIW FQNRRMKMKK INKDRAKDE

References

[1]	"Temporal colinearity in expression of anterior Hox genes in developing chick embryos." Gaunt S.J., Strachan L. Dev. Dyn. 207:270-280(1996) [PubMed: 8922526] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Embryo.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X97750 mRNA. Translation: CAA66331.1.
UniGene	Gga.649
3D structure databases
HSSP	HSSP built from PDB template 9ANT based on UniProtKB P02833.
SMR	Q98924. Positions 91-167.
ModBase	Search...
Genome annotation databases
Ensembl	ENSGALG00000019640. Gallus gallus. [Contig view]
Phylogenomic databases
HOGENOM	Q98924.
HOVERGEN	Q98924.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR012287. Homeodomain-rel. IPR006711. Hox9_act. IPR000047. HTH_lambrepressr. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. PF04617. Hox9_act. 1 hit. [Graphical view]
PRINTS	PR00024. HOMEOBOX. PR00031. HTHREPRESSR.
ProDom	PD000010. Homeobox. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00389. HOX. 1 hit. [Graphical view]
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

HXA9_CHICK

Accession

Primary (citable) accession number: Q98924

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	July 22, 2008
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)