Reviewed, UniProtKB/Swiss-Prot Q9ASI1 (NIP41_ORYSJ)

Names and origin

Protein names

Recommended name:
    Aquaporin NIP4-1
Alternative name(s):
    NOD26-like intrinsic protein 4-1
    OsNIP4;1

Gene names

Name:	NIP4-1
Ordered Locus Names:	Os01g0112400, LOC_Os01g02190
ORF Names:	OSJNBb0032H19.9, P0439B06.35

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	286 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Aquaporins facilitate the transport of water and small neutral solutes across cell membranes By similarity.
Subcellular location	Membrane; Multi-pass membrane proteinProbable.
Tissue specificity	Expressed in leaves and at lower levels in roots.
Domain	Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
Sequence similarities	Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP subfamily. [View classification]

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane
Domain	Repeat Transmembrane
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 286	286	Aquaporin NIP4-1
Regions
	Transmembrane	59 – 79	21	1 Potential
	Transmembrane	86 – 106	21	2 Potential
	Transmembrane	133 – 153	21	3 Potential
	Transmembrane	173 – 193	21	4 Potential
	Transmembrane	201 – 221	21	5 Potential
	Transmembrane	241 – 261	21	6 Potential
	Motif	112 – 114	3	NPA 1
	Motif	227 – 229	3	NPA 2
	Compositional bias	36 – 42	7	Poly-Ala
Experimental info
	Sequence conflict	190	1	A → V in AK106825. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q9ASI1-1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: E3E1A7FD2C9FE54E	FASTA	286	29,806
	10 20 30 40 50 60 MTTDHAGKKV DVVVVGNVDG EHVGVEQARH DLHEEAAAAA AADHHATRGL AIGFLIREVM 70 80 90 100 110 120 VEGLASFLVV FWSCVAALMQ EMYGTLTFPM VCLVVAMTVA FVLSWLGPAH FNPAVTITFA 130 140 150 160 170 180 AYRRFPVWPK LPLYVAAQLA GSLLACLSVN AVMRPRHDHF YGTAPVVVHG TRLPFLMEFL 190 200 210 220 230 240 ASAVLMIVIA TVATDGTAGK TVGGIAIGAA VGGLGLVIGP VSGGSMNPAR TLGPAIVLGR 250 260 270 280 YDGVWIYVVA PVAGMLVGAL CNRAVRLSHR IVAFLCGTSV GIAGSP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence and structure of rice chromosome 1." Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T. Nature 420:312-316(2002) [PubMed: 12447438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana." The rice annotation project (RAP) Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[5]	"Identification of 33 rice aquaporin genes and analysis of their expression and function." Sakurai J., Ishikawa F., Yamaguchi T., Uemura M., Maeshima M. Plant Cell Physiol. 46:1568-1577(2005) [PubMed: 16033806] [Abstract] Cited for: NOMENCLATURE, TISSUE SPECIFICITY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP002882 Genomic DNA. Translation: BAB39896.1. AP003219 Genomic DNA. Translation: BAB61180.1. AP008207 Genomic DNA. Translation: BAF03727.1. AK106825 mRNA. No translation available.
RefSeq	NP_001041813.1.
UniGene	Os.31744
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4326119.
KEGG	osa:4326119.
NMPDR	fig|39947.1.peg.852.
Organism-specific databases
Gramene	Q9ASI1.
Family and domain databases
InterPro	IPR000425. MIP. [Graphical view]
Gene3D	G3DSA:1.20.1080.10. MIP. 1 hit.
PANTHER	PTHR19139. MIP. 1 hit.
Pfam	PF00230. MIP. 1 hit. [Graphical view]
PRINTS	PR00783. MINTRINSICP.
ProDom	PD000295. MIP. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00221. MIP. 1 hit. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

NIP41_ORYSJ

Accession

Primary (citable) accession number: Q9ASI1

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 2007
Last sequence update:	June 1, 2001
Last modified:	July 22, 2008
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)