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Reviewed, UniProtKB/Swiss-Prot Q9BR61 (ACBD6_HUMAN)

Last modified July 22, 2008. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Acyl-CoA-binding domain-containing protein 6
Gene names
Name: ACBD6
OrganismHomo sapiens (Human)
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Sequence similarities

Contains 1 ACB (acyl-CoA-binding) domain.

Contains 2 ANK repeats.

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Ontologies

Keywords

   DomainANK repeat
Repeat
   PTMPhosphoprotein
   Technical term3D-structure

Gene Ontology (GO)

None. [Check GOA]

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical view

Molecule processing

Chain1 – 282282Acyl-CoA-binding domain-containing protein 6

Regions

Domain42 – 12786ACB
Repeat191 – 22030ANK 1
Repeat224 – 25330ANK 2

Amino acid modifications

Modified residue691Phosphotyrosine By similarity

Secondary structure

1 ........... 282
Helix Strand Turn

Details...

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Sequences

Sequence LengthMass (Da)Tools
Q9BR61-1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 0EA01CFDB5C5ECB2

FASTA28231,151
        10         20         30         40         50         60 
MASSFLPAGA ITGDSGGELS SGDDSGEVEF PHSPEIEETS CLAELFEKAA AHLQGLIQVA 

        70         80         90        100        110        120 
SREQLLYLYA RYKQVKVGNC NTPKPSFFDF EGKQKWEAWK ALGDSSPSQA MQEYIAVVKK 

       130        140        150        160        170        180 
LDPGWNPQIP EKKGKEANTG FGGPVISSLY HEETIREEDK NIFDYCRENN IDHITKAIKS 

       190        200        210        220        230        240 
KNVDVNVKDE EGRALLHWAC DRGHKELVTV LLQHRADINC QDNEGQTALH YASACEFLDI 

       250        260        270        280 
VELLLQSGAD PTLRDQDGCL PEEVTGCKTV SLVLQRHTTG KA

« Hide

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References

« Hide 'large scale' references
[1]"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
Nature 441:315-321(2006) [PubMed: 16710414] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Lung.
[3]"Solution structure of RSGI RUH-040, an ACBP domain from human cDNA."
RIKEN structural genomics initiative (RSGI)
Submitted (NOV-2005) to the PDB data bank
Cited for: STRUCTURE BY NMR OF 42-137.

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Cross-references

Sequence databases

AL445469, AL139141, AL358354 Genomic DNA. Translation: CAH71747.1.
AL139141, AL358354, AL445469 Genomic DNA. Translation: CAI19365.1.
AL358354, AL139141, AL445469 Genomic DNA. Translation: CAI15093.1.
BC006505 mRNA. Translation: AAH06505.1.
RefSeqNP_115736.1.
UniGeneHs.200051

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
2COPNMR-A40-137[»]
ModBaseSearch...

PTM databases

PhosphoSiteQ9BR61.

Genome annotation databases

EnsemblENSG00000135847. Homo sapiens. [Contig view]
GeneID84320.
KEGGhsa:84320.

Organism-specific databases

HGNCHGNC:23339. ACBD6.
PharmGKBPA134925459.
GenAtlasSearch...
GeneCardsSearch...

Phylogenomic databases

HOGENOMQ9BR61.
HOVERGENQ9BR61.

Gene expression databases

ArrayExpressQ9BR61.
CleanExHS_ACBD6.
GermOnlineENSG00000135847. Homo sapiens.

Family and domain databases

InterProIPR000582. Acyl-CoA-binding_protein.
IPR002110. ANK.
IPR014352. FERM/acyl-CoA_bd_prot_3-hlx.
[Graphical view]
Gene3DG3DSA:1.20.80.10. ACBP. 1 hit.
G3DSA:1.25.40.20. ANK. 1 hit.
PfamPF00887. ACBP. 1 hit.
PF00023. Ank. 2 hits.
[Graphical view]
PRINTSPR00689. ACOABINDINGP.
PR01415. ANKYRIN.
ProDomPD351532. Ac_coA_bind_prot. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00248. ANK. 2 hits.
[Graphical view]
PROSITEPS00880. ACB_1. False negative.
PS51228. ACB_2. 1 hit.
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
[Graphical view]
BLOCKSSearch...

Other Resources

ProtoNetSearch...

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Entry information

Entry nameACBD6_HUMAN
AccessionPrimary (citable) accession number: Q9BR61
Entry history
Integrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: June 1, 2001
Last modified: July 22, 2008
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

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Relevant documents

Human chromosome 1

Human chromosome 1: entries, gene names and cross-references to MIM

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents