Reviewed, UniProtKB/Swiss-Prot Q9H560 (ANR19_HUMAN)

Names and origin

Protein names

Recommended name:
    Ankyrin repeat domain-containing protein 19

Gene names

Name:

ANKRD19

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 5 ANK repeats.

Ontologies

Keywords
Domain	ANK repeat Repeat
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 264	264	Ankyrin repeat domain-containing protein 19
Regions
	Repeat	67 – 96	30	ANK 1
	Repeat	100 – 129	30	ANK 2
	Repeat	133 – 162	30	ANK 3
	Repeat	166 – 195	30	ANK 4
	Repeat	199 – 228	30	ANK 5

Sequences

	Sequence		Length	Mass (Da)
	Q9H560-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: AB9237C94CAC0405	FASTA	264	30,436
	10 20 30 40 50 60 MRKLFSFGRR LGQALLDSMD QEYAGRGYHI RDWELRKIHR AAIKGDAAEV EHCLTRRFRD 70 80 90 100 110 120 LDARDRKDRT VLHLTCAHGR VEVVTLLLSR RCQINIYDRL NRTPLMKAVH CQEEACAIIL 130 140 150 160 170 180 LEHGANPNIK DIYSNTALHY AVYNKGTSLA EKLLSHHANI EALNEEGNTP LLFAINSRRQ 190 200 210 220 230 240 QIVEFLLKNQ ANLHAIDNFR RTALMLAVQH NSSSIVSLLL QQNINIFSQD LFGQTAEDYA 250 260 VCYNFRSIQQ QILEHKNKIL KSHL

References

[1]

"DNA sequence and analysis of human chromosome 9." Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I. Nature 429:369-374(2004) [PubMed: 15164053] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain, Brain cortex and Testis.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL136981 Genomic DNA. No translation available. BC028712 mRNA. Translation: AAH28712.1. BC038951 mRNA. Translation: AAH38951.1. BC117367 mRNA. Translation: AAI17368.1.
UniGene	Hs.643597
3D structure databases
HSSP	HSSP built from PDB template 1K1B based on UniProtKB P20749.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000127098. Homo sapiens. [Contig view] ENSG00000218940. Homo sapiens. [Contig view]
NMPDR	fig|9606.3.peg.31547.
Organism-specific databases
HGNC	HGNC:22567. ANKRD19.
PharmGKB	PA134991046.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOGENOM	Q9H560.
HOVERGEN	Q9H560.
Gene expression databases
ArrayExpress	Q9H560.
CleanEx	HS_ANKRD19.
Family and domain databases
InterPro	IPR002110. ANK. [Graphical view]
Gene3D	G3DSA:1.25.40.20. ANK. 1 hit.
Pfam	PF00023. Ank. 6 hits. [Graphical view]
PRINTS	PR01415. ANKYRIN.
SMART	SM00248. ANK. 6 hits. [Graphical view]
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 4 hits. [Graphical view]
ProDom	Q9H560. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

ANR19_HUMAN

Accession

Primary (citable) accession number: Q9H560
Secondary accession number(s): Q17RD3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	March 1, 2001
Last modified:	September 23, 2008
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)