Reviewed, UniProtKB/Swiss-Prot Q9NZ32 (ARP10_HUMAN)

Names and origin

Protein names

Recommended name:
    Actin-related protein 10
      Short name=hARP11

Gene names

Name:	ACTR10
Synonyms:	ACTR11, ARP11

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	417 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Cytoplasm › cytoskeletonBy similarity.
Sequence similarities	Belongs to the actin family.

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton
Molecular function	Structural protein
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 417	417	Actin-related protein 10
Experimental info
	Sequence conflict	53	1	R → K in BAA91243. Ref.2
	Sequence conflict	93	1	E → K in BAA91243. Ref.2
	Sequence conflict	219	1	D → G in BAB14083. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q9NZ32-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: DF351A7B299DB7C1	FASTA	417	46,307
	10 20 30 40 50 60 MPLYEGLGSG GEKTAVVIDL GEAFTKCGFA GETGPRCIIP SVIKRAGMPK PVRVVQYNIN 70 80 90 100 110 120 TEELYSYLKE FIHILYFRHL LVNPRDRRVV IIESVLCPSH FRETLTRVLF KYFEVPSVLL 130 140 150 160 170 180 APSHLMALLT LGINSAMVLD CGYRESLVLP IYEGIPVLNC WGALPLGGKA LHKELETQLL 190 200 210 220 230 240 EQCTVDTSVA KEQSLPSVMG SVPEGVLEDI KARTCFVSDL KRGLKIQAAK FNIDGNNERP 250 260 270 280 290 300 SPPPNVDYPL DGEKILHILG SIRDSVVEIL FEQDNEEQSV ATLILDSLIQ CPIDTRKQLA 310 320 330 340 350 360 ENLVVIGGTS MLPGFLHRLL AEIRYLVEKP KYKKALGTKT FRIHTPPAKA NCVAWLGGAI 370 380 390 400 410 FGALQDILGS RSVSKEYYNQ TGRIPDWCSL NNPPLEMMFD VGKTQPPLMK RAFSTEK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A novel gene expressed in human hypothalamus." Xiao H., Song H., Gao G., Ren S., Chen Z., Han Z. Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Hypothalamus.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Ovary.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF220190 mRNA. Translation: AAF67655.1. AK000544 mRNA. Translation: BAA91243.1. AK022534 mRNA. Translation: BAB14083.1. BC011997 mRNA. Translation: AAH11997.1.
RefSeq	NP_060947.1.
UniGene	Hs.509451
3D structure databases
HSSP	HSSP built from PDB template 1K8K based on UniProtKB P32391.
ModBase	Search...
PTM databases
PhosphoSite	Q9NZ32.
Genome annotation databases
Ensembl	ENSG00000131966. Homo sapiens. [Contig view]
GeneID	55860.
KEGG	hsa:55860.
Organism-specific databases
HGNC	HGNC:17372. ACTR10.
PharmGKB	PA134899463.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOGENOM	Q9NZ32.
HOVERGEN	Q9NZ32.
Gene expression databases
ArrayExpress	Q9NZ32.
CleanEx	HS_ACTR10.
GermOnline	ENSG00000131966. Homo sapiens.
Family and domain databases
InterPro	IPR004000. Actin_like. [Graphical view]
PANTHER	PTHR11937. Actin_like. 1 hit.
Pfam	PF00022. Actin. 1 hit. [Graphical view]
SMART	SM00268. ACTIN. 1 hit. [Graphical view]
ProDom	Q9NZ32. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

ARP10_HUMAN

Accession

Primary (citable) accession number: Q9NZ32
Secondary accession number(s): Q9H9Y5, Q9NWY2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 27, 2003
Last sequence update:	October 1, 2000
Last modified:	July 22, 2008
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)