Reviewed, UniProtKB/Swiss-Prot Q9PWD6 (HXA10_MORSA)

Names and origin

Protein names

Recommended name:
    Homeobox protein Hox-A10

Gene names

Name:

hoxa10

Organism

Morone saxatilis (Striped bass)

Taxonomic identifier

34816 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Perciformes › Percoidei › Moronidae › Morone

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.
Subcellular location	NucleusBy similarity.
Sequence similarities	Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Homeobox
Ligand	DNA-binding
Molecular function	Developmental protein
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 289	289	Homeobox protein Hox-A10
Regions
	DNA binding	215 – 274	60	Homeobox
	Compositional bias	78 – 85	8	Poly-Gly

Sequences

	Sequence		Length	Mass (Da)
	Q9PWD6-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 101BF0669A14CED8	FASTA	289	32,252
	10 20 30 40 50 60 MSSMEMWMDA QRSCRMDQEH PVGPQVAPCS FPQNIKEEST YCLYEQPKCP KASTAEDLTY 70 80 90 100 110 120 SRLTTTGLGS STCTVTDGGG GGGGGSVPVP GYFRLSQTHA HSHKLYNTNG PQPNPSHSHF 130 140 150 160 170 180 GLHPTAPARF HTPPTSTSTP ATAQEGRNTE EPVSSGNADL QPHAAPGTEE ARESSDAEVS 190 200 210 220 230 240 SADETEEHDK ERQAKSTKGD TKSENTANWL TAKSGRKKRC PYTKHQTLEL EKEFLFNMYL 250 260 270 280 TRERRLEISK SVHLTDRQVK IWFQNRRMKL KKMTRENRIR ELTSNYGFS

References

[1]	"Genomic organization of the Hoxa4-Hoxa10 region from Morone saxatilis: implications for Hox gene evolution among vertebrates." Snell E.A., Scemama J.L., Stellwag E.J. J. Exp. Zool. 285:41-49(1999) [PubMed: 10327649] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF089743 Genomic DNA. Translation: AAD46395.1.
3D structure databases
HSSP	HSSP built from PDB template 9ANT based on UniProtKB P02833.
SMR	Q9PWD6. Positions 207-276.
ModBase	Search...
Phylogenomic databases
HOVERGEN	Q9PWD6.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR012287. Homeodomain-rel. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. [Graphical view]
PRINTS	PR00024. HOMEOBOX.
ProDom	PD000010. Homeobox. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00389. HOX. 1 hit. [Graphical view]
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

HXA10_MORSA

Accession

Primary (citable) accession number: Q9PWD6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2001
Last sequence update:	May 1, 2000
Last modified:	July 22, 2008
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)