Reviewed, UniProtKB/Swiss-Prot Q9U2D9 (GYS_CAEEL)

Names and origin

Protein names

Recommended name:
    Probable glycogen [starch] synthase
    EC=2.4.1.11

Gene names

Name:	gsy-1
ORF Names:	Y46G5A.31

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	672 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Transfers the glycosyl residue from UDPG to the non-reducing end of alpha-1,4-glucan.
Catalytic activity	UDP-glucose ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha-D-glucosyl)(n+1).
Pathway	Glycan biosynthesis; glycogen biosynthesis.
Sequence similarities	Belongs to the mammalian/fungal glycogen synthase family.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	body morphogenesis Inferred from mutant phenotype. Source: WormBase embryonic development ending in birth or egg hatching Inferred from mutant phenotype. Source: WormBase locomotion Inferred from mutant phenotype. Source: WormBase nematode larval development Inferred from mutant phenotype. Source: WormBase
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
gei-16	Q22534	1	EBI-313125,EBI-327642
gei-4	Q9TZ38	1	EBI-313125,EBI-329192
pmk-1	Q17446	1	EBI-313125,EBI-312987
sdz-38	Q09620	1	EBI-313125,EBI-332504
taf-9	O45784	1	EBI-313125,EBI-327711

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 672	672	Probable glycogen [starch] synthase		PRO_0000194770
Sites
	Binding site	56	1	UDP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9U2D9-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 3B3C3E9044CAC8A0	FASTA	672	76,459
	10 20 30 40 50 60 MPDHARMPRN LSSNKIAKTI AGEDLDEEEV LEMDAGQSAR EEGRFVFECA WEVANKVGGI 70 80 90 100 110 120 YTVLRSKAQI STEELGDQYC MFGPMKDGKW RLEVDPIEPE NRTIRAAMKR FQADGFRCMY 130 140 150 160 170 180 GRWLIEGYPK VILFDLGSGA VKMNEWKHEL FEQCKIGIPH EDIESNDAVI LGFMVALFLK 190 200 210 220 230 240 HFRESVTSYT PLVVAHFHEW QAGVGLLMTR LWKLDIATVY TTHATLLGRH LCAGGADLYN 250 260 270 280 290 300 NLDSFDLDAE AGKRKIYHQY CLERAACQTA HIFTTVSEIT GLEAEHFLCR KPDVLTPNGL 310 320 330 340 350 360 NVVKFAALHE FQNLHAQNKE KINQFIRGHF HGHLDFDLDK TLYFFTAGRY EFSNKGGDMF 370 380 390 400 410 420 IESLARLNHY LKTTSDPRHM GVTVVAFLIY PAPANSFNVE SLKGQAVTKQ LKEAVDRIKE 430 440 450 460 470 480 KVGQRIFDIC LQGHLPEPEE LMSPADNILL KRCIMSLHNS SLPPICTHNM IRADDPVLES 490 500 510 520 530 540 LRRTSLFNKP EDRVKVVFHP EFLSSVSPLI GLDYEDFVRG CHLGVFPSYY EPWGYTPAEC 550 560 570 580 590 600 TVMGIPSVST NLSGFGCFMQ EHVEDHEQKG IYVIDRRHKA AEESVQELAQ VMYDFCGQSR 610 620 630 640 650 660 RQRIILRNSN EGLSALLDWQ NLGVFYRDCR RLALERLHPD VDKIMRDNEG KVPSAATSRR 670 PSIHSSDGED DE

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL110485 Genomic DNA. Translation: CAB60373.1.
RefSeq	NP_496736.1.
UniGene	Cel.7404
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9U2D9.
Genome annotation databases
Ensembl	Y46G5A.31. Caenorhabditis elegans. [Contig view]
GeneID	174924.
KEGG	cel:Y46G5A.31.
NMPDR	fig|6239.3.peg.7868.
Organism-specific databases
WormBase	WBGene00001793. gsy-1.
WormPep	Y46G5A.31. CE24302. [WorfDB]
Gene expression databases
ArrayExpress	Q9U2D9.
Family and domain databases
InterPro	IPR008631. Glycogen_synth. [Graphical view]
PANTHER	PTHR10176. Glycogen_synth. 1 hit.
Pfam	PF05693. Glycogen_syn. 1 hit. [Graphical view]
BLOCKS	Search...
ProtoNet	Search...
Other Resources
NextBio	886062.

Entry information

Entry name

GYS_CAEEL

Accession

Primary (citable) accession number: Q9U2D9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 11, 2001
Last sequence update:	May 1, 2000
Last modified:	November 4, 2008
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project